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NCT04179903: ACTLIFE
Efficacy and Safety of the Physical Activity Program in Women With Post-menopausal Osteoporosis
NA trial testing Physical activity in Osteoporosis, Postmenopausal in 52 participants. Completed in 30 June 2021.
30 September 2020
Quick facts
| Lead sponsor | Istituto Ortopedico Rizzoli |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | other |
| Enrollment | 52 |
| Start date | 1 February 2019 |
| Primary completion | 30 September 2020 |
| Estimated completion | 30 June 2021 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Physical activity
Conditions studied
- Osteoporosis, Postmenopausal — all drugs for Osteoporosis, Postmenopausal →
- Physical Activity — all drugs for Physical Activity →
Sponsor
Istituto Ortopedico Rizzoli — full company profile →
Who can join
40 and older, female only, with Osteoporosis, Postmenopausal or Physical Activity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study will be single blinded since professionals who will evaluate patients will not know to which exercise group patients have been assigned. The investigators hypothesize that effectiveness and safety of the exercise program are equal when administered as gym trainer or individual home trainer. However, the investigators expect differences in adherence among the two groups which may cause different impact on the outcome measures. Given the large amount of evidence on the efficacy of Physical Activity in women with Osteoporosis, the investigators considered it ethically unacceptable to advise a control group inactivity. On the other hand, it seemed particularly relevant for the purpose of addressing the advice to the improvement of the active lifestyle, to evaluate the impact of the ACTLIFE exercise program when administered as gym trainer or individual home trainer
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
A Randomized Clinical Trial to Evaluate the Efficacy and Safety of the ACTLIFE Exercise Program for Women with Post-menopausal Osteoporosis: Study Protocol.
Bragonzoni L, Barone G, Benvenuti F, Canal V, et al · · 2020 · cited 7× · PMID 32012966 · DOI 10.3390/ijerph17030809 -
Influence of Coaching on Effectiveness, Participation, and Safety of an Exercise Program for Postmenopausal Women with Osteoporosis: A Randomized Trial.
Bragonzoni L, Barone G, Benvenuti F, Ripamonti C, et al · · 2023 · cited 4× · PMID 36777456 · DOI 10.2147/cia.s389967 -
Effects of COVID-19 Lockdown on Adherence to Individual Home- or Gym-Based Exercise Training among Women with Postmenopausal Osteoporosis.
Pinelli E, Barone G, Marini S, Benvenuti F, et al · · 2021 · cited 4× · PMID 33801389 · DOI 10.3390/ijerph18052441
Verify or expand the search:
- PubMed search for NCT04179903
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Physical activity
Trials testing the same drug.
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- NCT07104669 — Sports Nutrition Assessment Program · not yet recruiting
- NCT06541977 — A New Model of Exercise Referral Scheme Before and After Bariatric Surgery for People With Obesity · NA · not yet recruiting
- NCT06817980 — Disorders of the Sense of Self and Physical Activity · NA · not yet recruiting
- NCT07140536 — The Impact of Treadmills and Cooler Environments for Office Workplaces on Ergonomics, Heating Energy Requirements, Perfo · NA · completed
Other recruiting trials for Osteoporosis, Postmenopausal
Currently open trials in the same condition.
- NCT07242612 — Bone Turnover Markers and Treatment Efficacy in Postmenopausal Osteoporosis · NA · recruiting
- NCT06558188 — Combined Anabolic Therapy · Phase 4 · recruiting
- NCT06655701 — Stress Urinary Incontinence and Sarcopenia in Postmenopausal Osteoporosis · recruiting
- NCT06525688 — New Biomarkers and Therapeutic Targets in Osteoporosis Via Omics Technologies · recruiting
- NCT05655013 — Treatment With Zoledronate Subsequent to Denosumab in Osteoporosis 2 (ZOLARMAB2) · Phase 4 · active not recruiting
Other Istituto Ortopedico Rizzoli trials
Trials by the same sponsor.
- NCT07590882 — Evaluation of Return to Sports Activity After Periacetabular Osteotomy: An Observational Study · enrolling by invitation
- NCT07021222 — Multifactorial Strategies for the Prevention of the Risks of Ulceration in Patients Affected by Diabetic Foot (DARE-DiaF · NA · recruiting
- NCT07360964 — Clear Cell Chondrosarcoma in Italy · NA · active not recruiting
- NCT07140367 — "Transarterial Microembolization (TAME) in Inflammatory Knee Pathology" · recruiting
- NCT07102875 — Ready to Sail 2: A Pilot Study of Sail-Assisted Telerehabilitation in Rare Skeletal Diseases · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04179903 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istituto Ortopedico Rizzoli
- Last refreshed: 26 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04179903.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing