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NCT04177433
The Use of Intra-articular Corticosteroid Injection to Treat Osteoarthritis of the Carpometacarpal Joint
Phase 4 trial testing Depo-Medrol Injectable Product in Osteoarthritis of the Carpometacarpal Joint in 61 participants. Completed in 31 December 2025.
29 September 2025
Quick facts
| Lead sponsor | University of Alberta |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 61 |
| Start date | 2 December 2020 |
| Primary completion | 29 September 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Depo-Medrol Injectable Product — full drug profile →
- Saline
Conditions studied
- Osteoarthritis of the Carpometacarpal Joint — all drugs for Osteoarthritis of the Carpometacarpal Joint →
- Thumb Osteoarthritis — all drugs for Thumb Osteoarthritis →
Sponsor
University of Alberta
Who can join
18 and older, any sex, with Osteoarthritis of the Carpometacarpal Joint or Thumb Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized clinical trial (RCT) will evaluate 6-month outcomes following intra-articular injections for arthritis of the thumb carpometacarpal (CMC) joint by comparing corticosteroid plus local anesthetic versus saline (placebo) plus local anesthetic.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04177433
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04177433 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Alberta
- Last refreshed: 2 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04177433.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing