NCT04174209 (RE-CON) is a NA clinical trial of Cylinder in Keratoconus, sponsored by University Hospital, Clermont-Ferrand.

Who is sponsoring NCT04174209?

NCT04174209 is sponsored by University Hospital, Clermont-Ferrand.

What drugs are being tested in NCT04174209?

Interventions in NCT04174209: Cylinder, Dial, Slit.

What condition does NCT04174209 study?

NCT04174209 studies Keratoconus, Alteration of Visual Acuity.

Is NCT04174209 still recruiting?

NCT04174209 is currently completed. Last updated 20 March 2020.

Last reviewed 2020-03-20 · How we verify

NCT04174209: RE-CON

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

CHOICE OF SUBJECTIVE OCULAR REFRACTION TECHNIQUE AND CORNEAL TOPOGRAPHY OF KERATOCONUS

Completed NA Last updated 20 March 2020

What this trial tests

NA trial testing Cylinder in Keratoconus in 52 participants. Completed in 6 March 2020.

Timeline

18 November 2019

Primary endpoint
6 March 2020

6 March 2020

Quick facts

Lead sponsor	University Hospital, Clermont-Ferrand
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	52
Start date	18 November 2019
Primary completion	6 March 2020
Estimated completion	6 March 2020
Sites	1 location across France

Drugs / interventions tested

Cylinder
Dial
Slit

Conditions studied

Keratoconus — all drugs for Keratoconus →
Alteration of Visual Acuity — all drugs for Alteration of Visual Acuity →

Sponsor

University Hospital, Clermont-Ferrand

Who can join

18 and older, any sex, with Keratoconus or Alteration of Visual Acuity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Keratoconus is a rare evolving corneal ectasia that alters visual acuity. To improve spectacle-corrected visual acuity, various subjective refraction techniques can be used. The subjective refraction techniques of keratoconus-carrying patients have never been studied. The main hypothesis is that the most suitable subjective ocular refraction method varies with the corneal topography of the keratoconus. The main objective is to define the most appropriate refractive technique(s) based on corneal topographies in order to provide keratoconus-affected patients with the best spectacle-corrected visual acuity.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Benefits of using corneal topography to choose subjective refraction technique in keratoconus (RE-CON): a prospective comparative crossover clinical study.
Metzger M, Navel V, Barrière JV, Kwiatkowski F, et al · · 2022 · cited 1× · PMID 34415365 · DOI 10.1007/s00417-021-05382-y

Verify or expand the search:

Other recruiting trials for Keratoconus

Currently open trials in the same condition.

NCT07372911 — PRoTECT: Corneal Wavefront Guided PRK + Epi-off CXL vs. PTK+Epi-off CXL in Keratoconus · NA · recruiting
NCT07461129 — Electrophysiological Changes in Cases of Different Stages of Keratoconus · active not recruiting
NCT06601101 — Effects of Topical Insulin on Corneal Epithelium Healing After Corneal Crosslinking in Patients With Keratoconus · Phase 3 · recruiting
NCT05516004 — Safety and Effectiveness of the PXL-Platinum 330 System for Cornea Crosslinking in Eyes With Cornea Thinning · Phase 2 · recruiting
NCT06798779 — Predicting Manifest Astigmatism in Keratoconus Patients. · active not recruiting

Other University Hospital, Clermont-Ferrand trials

Trials by the same sponsor.

NCT07179276 — Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock · NA · recruiting
NCT07476768 — PAINDYS_Characterizing Pain in Fibrous Dysplasia of Bone/McCune-Albright Syndrome: an Exploratory Pilot Study · NA · not yet recruiting
NCT07439146 — Risk of Pneumonia in Intubated Patients in Emergency Situations · not yet recruiting
NCT07427537 — Exploration of Circulating microRNAs as Biomarkers of Chemo-induced Peripheral Neuropathy: a Study in Cancer Patients · NA · recruiting
NCT07330856 — Evaluation of Treatments for Dry or Productive Cough · Phase 4 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04174209 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital, Clermont-Ferrand
Last refreshed: 20 March 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04174209.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing