Last reviewed · How we verify
NCT04168970: LIVE
Percutaneous Left Stellate Ganglion Block In Out-of-hospital Cardiac Arrest Due to Refractory VEntricular Arrhythmias (LIVE Study)
trial testing PSGB in Out-Of-Hospital Cardiac Arrest in 53 participants. Status unknown.
31 July 2025
Quick facts
| Lead sponsor | Fondazione IRCCS Policlinico San Matteo di Pavia |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 53 |
| Start date | 15 July 2019 |
| Primary completion | 31 July 2025 |
| Estimated completion | 31 July 2025 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- PSGB
Conditions studied
- Out-Of-Hospital Cardiac Arrest — all drugs for Out-Of-Hospital Cardiac Arrest →
- Ventricular Fibrillation Sustained — all drugs for Ventricular Fibrillation Sustained →
Sponsor
Fondazione IRCCS Policlinico San Matteo di Pavia
Who can join
Adults 18 to 100, any sex, with Out-Of-Hospital Cardiac Arrest or Ventricular Fibrillation Sustained. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A prospective uncontrolled study to verify the feasibility and practicability of percutaneous stellate ganglion block (PSGB) in patient suffering from a refractory out-of-hospital cardiac arrest (OHCA) due to a shockable rhythm and the eventual occurrence of complication related to it. The study will also assess whether the rate of return of spontaneous circulation (ROSC) until admission and transfer of care to the receiving hospital is higher in the patients treated with PSGB as compared to historical controls.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Continuous stellate ganglion block for ventricular arrhythmias: case series, systematic review, and differences from thoracic epidural anaesthesia.
Dusi V, Angelini F, Baldi E, Toscano A, et al · · 2024 · cited 17× · PMID 38531027 · DOI 10.1093/europace/euae074 -
Neuromodulatory Approaches for Atrial Fibrillation Ablation.
Rodríguez-Mañero M, Martínez-Sande JL, García-Seara J, González-Ferrero T, et al · · 2021 · cited 1× · PMID 35024055 · DOI 10.15420/ecr.2021.05
Verify or expand the search:
- PubMed search for NCT04168970
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Out-Of-Hospital Cardiac Arrest
Currently open trials in the same condition.
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- NCT06203847 — The Effect of Prehospital Combination of Epinephrine, Vasopressin, and Steroid in OHCA · NA · recruiting
- NCT06306625 — REmote COnditioning in Out-of-Hospital Cardiac Arrest · NA · recruiting
- NCT06071910 — Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest · NA · recruiting
Other Fondazione IRCCS Policlinico San Matteo di Pavia trials
Trials by the same sponsor.
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- NCT07494344 — Italian Retrospective/Prospective Observational Study on Prosthetic Surgery in Patients With Congenital Coagulation Dise · recruiting
- NCT07356583 — Neonatal Enterovirus Infections in Italy: Virological Characterization, Genomic and Clinical-epidemiological Insights on · recruiting
- NCT07435207 — Thrombotic RIsk FActors in AL-goneurodystrophy · enrolling by invitation
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04168970 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fondazione IRCCS Policlinico San Matteo di Pavia
- Last refreshed: 8 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04168970.
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