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NCT04167722: EXOPRO
How Does Prostate Cancer Metastasize? Studying the Role of Secreted Packages (Exosomes) From Fat Tissue in Lean and Obese Patients
trial testing Robotic Radical Prostatectomy in Prostate Cancer in 100 participants. Status unknown.
1 October 2023
Quick facts
| Lead sponsor | Imperial College London |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 1 October 2019 |
| Primary completion | 1 October 2023 |
| Estimated completion | 1 October 2024 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Robotic Radical Prostatectomy
Conditions studied
- Prostate Cancer — all drugs for Prostate Cancer →
- Obesity — all drugs for Obesity →
Sponsor
Imperial College London
Who can join
Eligibility, male only, with Prostate Cancer or Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators will be collecting prostate and fat tissue from participants undergoing radical prostatectomy to culture and study in the laboratory.
Publications & conference data
8 peer-reviewed publications reference this trial (live from Europe PMC):
-
Clinical applications of stem cell-derived exosomes.
Tan F, Li X, Wang Z, Li J, et al · · 2024 · cited 390× · PMID 38212307 · DOI 10.1038/s41392-023-01704-0 -
Cancer-Derived Exosomes: Their Role in Cancer Biology and Biomarker Development.
Kok VC, Yu CC. · · 2020 · cited 318× · PMID 33116515 · DOI 10.2147/ijn.s272378 -
Potential Use of Exosomes as Diagnostic Biomarkers and in Targeted Drug Delivery: Progress in Clinical and Preclinical Applications.
Huda MN, Nafiujjaman M, Deaguero IG, Okonkwo J, et al · · 2021 · cited 160× · PMID 33988964 · DOI 10.1021/acsbiomaterials.1c00217 -
Cancer nanotechnology: current status and perspectives.
Kemp JA, Kwon YJ. · · 2021 · cited 117× · PMID 34727233 · DOI 10.1186/s40580-021-00282-7 -
Clinical applications for exosomes: Are we there yet?
Perocheau D, Touramanidou L, Gurung S, Gissen P, et al · · 2021 · cited 101× · PMID 33751579 · DOI 10.1111/bph.15432 -
The impact of obesity on adipocyte-derived extracellular vesicles.
Kwan HY, Chen M, Xu K, Chen B. · · 2021 · cited 59× · PMID 34677643 · DOI 10.1007/s00018-021-03973-w -
Pathogenetic Features and Current Management of Glioblastoma.
Nguyen HM, Guz-Montgomery K, Lowe DB, Saha D. · · 2021 · cited 42× · PMID 33670551 · DOI 10.3390/cancers13040856 -
Adult Stem Cell-Derived Extracellular Vesicles in Cancer Treatment: Opportunities and Challenges.
Parfejevs V, Sagini K, Buss A, Sobolevska K, et al · · 2020 · cited 32× · PMID 32397238 · DOI 10.3390/cells9051171
Verify or expand the search:
- PubMed search for NCT04167722
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04167722 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Imperial College London
- Last refreshed: 22 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04167722.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing