NCT04165369 (Epis-AKI) is a clinical trial in Acute Kidney Injury (AKI), sponsored by University Hospital Muenster.

Who is sponsoring NCT04165369?

NCT04165369 is sponsored by University Hospital Muenster.

What condition does NCT04165369 study?

NCT04165369 studies Acute Kidney Injury (AKI).

Is NCT04165369 still recruiting?

NCT04165369 is currently completed. Last updated 21 July 2022.

Last reviewed 2022-07-21 · How we verify

NCT04165369: Epis-AKI

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Observational Study to Evaluate the Epidemiology of Surgical-induced Acute Kidney Injury

Completed Last updated 21 July 2022

What this trial tests

trial in Acute Kidney Injury (AKI) in 10,568 participants. Completed in 31 March 2022.

Timeline

9 June 2020

Primary endpoint
28 February 2022

31 March 2022

Quick facts

Lead sponsor	University Hospital Muenster
Status	Completed
Study type	OBSERVATIONAL
Enrollment	10,568
Start date	9 June 2020
Primary completion	28 February 2022
Estimated completion	31 March 2022
Sites	82 locations across France, Italy, Russia, Turkey (Türkiye), Saudi Arabia, Germany, Libya, Palestinian Territories

Conditions studied

Acute Kidney Injury (AKI) — all drugs for Acute Kidney Injury (AKI) →

Sponsor

University Hospital Muenster

Who can join

18 and older, any sex, with Acute Kidney Injury (AKI). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The evaluation of an accurate occurrence rate for AKI is of great importance for health policy, quality initiatives as well as for designing clinical trials. The primary objective is to prospectively evaluate the incidence of AKI within 72 h after extended surgical procedures that require admission to an observation unit.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Epidemiology of surgery associated acute kidney injury (EPIS-AKI): a prospective international observational multi-center clinical study.
Zarbock A, Weiss R, Albert F, Rutledge K, et al · · 2023 · cited 105× · PMID 37505258 · DOI 10.1007/s00134-023-07169-7
Acute kidney disease beyond day 7 after major surgery: a secondary analysis of the EPIS-AKI trial.
Meersch M, Weiss R, Strauß C, Albert F, et al · · 2024 · cited 22× · PMID 38285051 · DOI 10.1007/s00134-023-07314-2
EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI): study protocol for a multicentre, observational trial.
Weiss R, Saadat-Gilani K, Kerschke L, Wempe C, et al · · 2021 · cited 10× · PMID 35588372 · DOI 10.1136/bmjopen-2021-055705
Development of chronic kidney disease after major surgery
Meersch M, Weiss R, Strauß C, Albert F, et al · · 2023 · DOI 10.21203/rs.3.rs-3322920/v1

Verify or expand the search:

Other recruiting trials for Acute Kidney Injury (AKI)

Currently open trials in the same condition.

NCT07182422 — AST-120 (Kremezin®) for the Renal Protection and Attenuation of Decline in Acute Kidney Disease · Phase 4 · recruiting
NCT07101913 — Occurrence of Acute Kidney Injury After CAR-T Cells Treatments in B-cell Lymphoma. · active not recruiting

Other University Hospital Muenster trials

Trials by the same sponsor.

NCT07414498 — MICRO-SURG: Subgingival Microbiome in Peri-Implantitis, Regenerative, and Resective Periodontal Surgery · NA · not yet recruiting
NCT06999174 — Multiparametric MRI for Characterization of Hepatocellular Carcinoma · recruiting
NCT06980740 — Video-Tumorboard PLUS · recruiting
NCT06648733 — Improving Pharmacological Transition of Palliative Care Patients From Inpatient to Outpatient Care · NA · recruiting
NCT06464302 — Investigation of the Effect of Age and Injury Severity on Short-term Intra-hospital Outcomes After Surgical Stabilized R · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04165369 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital Muenster
Last refreshed: 21 July 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04165369.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing