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NCT04160143: PSPM

Post SBRT Pulmonary Metastasectomy (PSPM) Trial

Status unknown NA Last updated 25 February 2021
What this trial tests

NA trial testing Surgical resection and stereotactic body radiation therapy (SBRT) in Surgical Resection in 39 participants. Status unknown.

Timeline
14 July 2020
Primary endpoint
31 December 2023
31 December 2023

Quick facts

Lead sponsorMcMaster University
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment39
Start date14 July 2020
Primary completion31 December 2023
Estimated completion31 December 2023
Sites1 location across Canada

Drugs / interventions tested

Conditions studied

Sponsor

McMaster University

Who can join

18 and older, any sex, with Surgical Resection or Stereotactic Body Radiotherapy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this study is to determine the effectiveness of SBRT on reducing tumor viability at a pathologic level and also to evaluate the effects of combined modality treatment on low volume pulmonary metastases, in hopes of extrapolating this information to both primary and secondary lung cancer.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Redefining cancer care: harnessing circulating tumor cells' potential for improved diagnosis and prognosis.
    Janjua D, Chaudhary A, Joshi U, Tripathi T, et al · · 2025 · cited 4× · PMID 40676582 · DOI 10.1186/s12935-025-03883-y
  2. The histologic effects of neoadjuvant stereotactic body radiation therapy (SBRT) followed by pulmonary metastasectomy-rationale and protocol design for the Post SBRT Pulmonary Metastasectomy (PSPM) trial.
    Begum H, Swaminath A, Lee Y, Fahim C, et al · · 2022 · cited 4× · PMID 35571641 · DOI 10.21037/tcr-22-232

Verify or expand the search:

Other recruiting trials for Surgical Resection

Currently open trials in the same condition.

Other McMaster University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04160143.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing