Last reviewed · How we verify
NCT04160143: PSPM
Post SBRT Pulmonary Metastasectomy (PSPM) Trial
NA trial testing Surgical resection and stereotactic body radiation therapy (SBRT) in Surgical Resection in 39 participants. Status unknown.
31 December 2023
Quick facts
| Lead sponsor | McMaster University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 39 |
| Start date | 14 July 2020 |
| Primary completion | 31 December 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Surgical resection and stereotactic body radiation therapy (SBRT)
Conditions studied
- Surgical Resection — all drugs for Surgical Resection →
- Stereotactic Body Radiotherapy — all drugs for Stereotactic Body Radiotherapy →
- Lung Cancer — all drugs for Lung Cancer →
- Pulmonary Metastasectomy — all drugs for Pulmonary Metastasectomy →
Sponsor
McMaster University
Who can join
18 and older, any sex, with Surgical Resection or Stereotactic Body Radiotherapy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this study is to determine the effectiveness of SBRT on reducing tumor viability at a pathologic level and also to evaluate the effects of combined modality treatment on low volume pulmonary metastases, in hopes of extrapolating this information to both primary and secondary lung cancer.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Redefining cancer care: harnessing circulating tumor cells' potential for improved diagnosis and prognosis.
Janjua D, Chaudhary A, Joshi U, Tripathi T, et al · · 2025 · cited 4× · PMID 40676582 · DOI 10.1186/s12935-025-03883-y -
The histologic effects of neoadjuvant stereotactic body radiation therapy (SBRT) followed by pulmonary metastasectomy-rationale and protocol design for the Post SBRT Pulmonary Metastasectomy (PSPM) trial.
Begum H, Swaminath A, Lee Y, Fahim C, et al · · 2022 · cited 4× · PMID 35571641 · DOI 10.21037/tcr-22-232
Verify or expand the search:
- PubMed search for NCT04160143
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04160143 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by McMaster University
- Last refreshed: 25 February 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04160143.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing