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NCT04159285: PAUSE
Psychotherapeutic Augmentation of Brain Stimulation Effects
NA trial testing EffEKTiv 2.0 group CBT as continuation treatment after ECT in depressed patients in Depression Chronic in 16 participants. Completed in 15 June 2021.
1 May 2021
Quick facts
| Lead sponsor | Charite University, Berlin, Germany |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 16 |
| Start date | 5 January 2019 |
| Primary completion | 1 May 2021 |
| Estimated completion | 15 June 2021 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- EffEKTiv 2.0 group CBT as continuation treatment after ECT in depressed patients
- Treatment as usual
Conditions studied
- Depression Chronic — all drugs for Depression Chronic →
- Depression, Unipolar — all drugs for Depression, Unipolar →
- Treatment Resistant Depression — all drugs for Treatment Resistant Depression →
Sponsor
Charite University, Berlin, Germany
Who can join
18 and older, any sex, with Depression Chronic or Depression, Unipolar. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to investigate effectiveness and feasability of a 15-week group psychotherapeutic intervention as continuation treatment after electroconvulsive therapy in severely depressed patients. Feasibility and acceptance of the half-open manualized CBT intervention are assessed. Depressive symptoms, quality of life and emotion regulation skills will be assessed before ECT treatment, before and after the 15-week group CBT intervention and at a 6 months follow-up after treatment end and compared to depressed patients treated with ECT who did not partake in group CBT. Moreover, patients will attend two indidivual pre-group sessions with one of the group therapist and one individual post-group session
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
EffECTively Treating Depression: A Pilot Study Examining Manualized Group CBT as Follow-Up Treatment After ECT.
Carstens L, Hartling C, Aust S, Domke AK, et al · · 2021 · cited 2× · PMID 34539527 · DOI 10.3389/fpsyg.2021.723977
Verify or expand the search:
- PubMed search for NCT04159285
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Depression Chronic
Currently open trials in the same condition.
- NCT07422519 — Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant Depression · NA · recruiting
- NCT07082998 — Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression · NA · recruiting
Other Charite University, Berlin, Germany trials
Trials by the same sponsor.
- NCT07486167 — Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congeni · Phase 1, PHASE2 · not yet recruiting
- NCT07476729 — International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020) · Phase 3 · not yet recruiting
- NCT07503054 — Ovarian Cancer Screening and AI · NA · not yet recruiting
- NCT07529197 — Observational Study on Immunoadsorption (IA) in Patients With Autoantibody-Positive Post-Infectious ME/CFS · recruiting
- NCT07388693 — Feasibility of Integrating Olfactory Stimuli Into Virtual Reality Cue Exposure for Patients With Alcohol Dependence · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04159285 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Charite University, Berlin, Germany
- Last refreshed: 3 August 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04159285.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing