NCT04158284

Multicenter Registry for Patients With Childhood.Onset Craniopharyngioma, Xanthogranuloma, Cysts of Rathke's Pouch, Meningioma, Pituitary Adenoma, Arachnoid Cysts

Status unknown Last updated 7 March 2024

What this trial tests

trial in Craniopharyngioma in 90 participants. Status unknown.

Timeline

1 October 2019

Primary endpoint
30 June 2024

30 June 2024

Quick facts

Lead sponsor	Klinikum Oldenburg gGmbH
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	90
Start date	1 October 2019
Primary completion	30 June 2024
Estimated completion	30 June 2024
Sites	1 location across Germany

Conditions studied

• Craniopharyngioma — all drugs for Craniopharyngioma →
• Obesity — all drugs for Obesity →

Sponsor

Klinikum Oldenburg gGmbH

Who can join

Adults 1 Day to 18, any sex, with Craniopharyngioma or Obesity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

KRANIOPHARYNGEOM Registry 2019 will prospectively collect and descriptively analyse data on diagnostics, treatment, and follow-up of patients with craniopharyngioma. In continuation of preceding studies also patients with xanthogranuloma, meningioma, pituitary adenoma, prolactinoma and cystic intracranial malformations will be registered.

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

1. Outcome after pediatric craniopharyngioma: the role of age at diagnosis and hypothalamic damage.
   Beckhaus J, Friedrich C, Boekhoff S, Calaminus G, et al · · 2023 · cited 26× · PMID 36857103 · DOI 10.1093/ejendo/lvad027
2. Impact of parental body mass index at diagnosis on obesity in survivors of pediatric craniopharyngioma.
   Beckhaus J, Eveslage M, Bison B, Friedrich C, et al · · 2024 · cited 6× · PMID 38904467 · DOI 10.1530/ec-24-0126
3. Daytime sleepiness and health-related quality of life in patients with childhood-onset craniopharyngioma.
   Mann-Markutzyk LV, Beckhaus J, Özyurt J, Mehren A, et al · · 2025 · cited 4× · PMID 40108339 · DOI 10.1038/s41598-025-94384-5
4. Perinatally diagnosed congenital craniopharyngiomas in the KRANIOPHARYNGEOM trials.
   Beckhaus J, Boekhoff S, Scheinemann K, Schilling FH, et al · · 2023 · cited 3× · PMID 37878777 · DOI 10.1530/ec-23-0294
5. Sporadic and neurofibromatosis type 2-associated meningioma in children and adolescents.
   Wagener K, Beckhaus J, Boekhoff S, Friedrich C, et al · · 2023 · cited 2× · PMID 37402092 · DOI 10.1007/s11060-023-04344-0
6. Prolactin serum concentrations in childhood-onset craniopharyngioma patients.
   Sowithayasakul P, Beckhaus J, Özyurt J, Bison B, et al · · 2025 · PMID 40481916 · DOI 10.1007/s40618-025-02622-4