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NCT04156113

Effect of an Exercise on Serum Uncoupling Protein-1 Level and the Role of Uncoupling Protein-1-3826 A/G Polymorphism

Completed NA Last updated 9 September 2020
What this trial tests

NA trial testing Yo-Yo intermittent recovery test (level 1) in Uncoupling Protein-1 in 86 participants. Completed in 7 September 2020.

Timeline
11 November 2019
Primary endpoint
2 September 2020
7 September 2020

Quick facts

Lead sponsorEastern Mediterranean University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposebasic science
Enrollment86
Start date11 November 2019
Primary completion2 September 2020
Estimated completion7 September 2020
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Eastern Mediterranean University

Who can join

Adults 18 to 35, male only, with Uncoupling Protein-1 or Polymorphism, Restriction Fragment Length. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to determine the effect of an acute maximal exercise on serum uncoupling protein-1, irisin, interleukin 6 levels, and on blood lipid and lipoprotein concentrations. This study also evaluates the role of uncoupling protein-1-3826 A/G polymorphism on this eventual effect. Therefore, this study hypothesizes that: H01: Sedentary people and athletes' serum uncoupling protein 1, irisin, and interleukine 6 levels are different before and after an acute maximal exercise. H02: Sedentary people and athletes' basal serum uncoupling protein 1 levels are associated with uncoupling protein 1-3826 A/G polymorphism. H03: Uncoupling protein 1-3826 A/G polymorphism has a modifying role in the effect of maximal exercise on serum uncoupling protein 1 levels. H04: Sedentary people and athletes' basal serum lipid and lipoprotein levels are associated with uncoupling protein 1-3826 A/G polymorphism. H05: Uncoupling protein 1-3826 A / G polymorphism has a modifying role in the effect of maximal exercise on serum lipid and lipoprotein levels.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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