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NCT04156113
Effect of an Exercise on Serum Uncoupling Protein-1 Level and the Role of Uncoupling Protein-1-3826 A/G Polymorphism
NA trial testing Yo-Yo intermittent recovery test (level 1) in Uncoupling Protein-1 in 86 participants. Completed in 7 September 2020.
2 September 2020
Quick facts
| Lead sponsor | Eastern Mediterranean University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 86 |
| Start date | 11 November 2019 |
| Primary completion | 2 September 2020 |
| Estimated completion | 7 September 2020 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Yo-Yo intermittent recovery test (level 1)
Conditions studied
- Uncoupling Protein-1 — all drugs for Uncoupling Protein-1 →
- Polymorphism, Restriction Fragment Length — all drugs for Polymorphism, Restriction Fragment Length →
- Irisin — all drugs for Irisin →
Sponsor
Eastern Mediterranean University
Who can join
Adults 18 to 35, male only, with Uncoupling Protein-1 or Polymorphism, Restriction Fragment Length. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to determine the effect of an acute maximal exercise on serum uncoupling protein-1, irisin, interleukin 6 levels, and on blood lipid and lipoprotein concentrations. This study also evaluates the role of uncoupling protein-1-3826 A/G polymorphism on this eventual effect. Therefore, this study hypothesizes that: H01: Sedentary people and athletes' serum uncoupling protein 1, irisin, and interleukine 6 levels are different before and after an acute maximal exercise. H02: Sedentary people and athletes' basal serum uncoupling protein 1 levels are associated with uncoupling protein 1-3826 A/G polymorphism. H03: Uncoupling protein 1-3826 A/G polymorphism has a modifying role in the effect of maximal exercise on serum uncoupling protein 1 levels. H04: Sedentary people and athletes' basal serum lipid and lipoprotein levels are associated with uncoupling protein 1-3826 A/G polymorphism. H05: Uncoupling protein 1-3826 A / G polymorphism has a modifying role in the effect of maximal exercise on serum lipid and lipoprotein levels.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04156113
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04156113 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Eastern Mediterranean University
- Last refreshed: 9 September 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04156113.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing