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NCT04151147
Effect of CGF on Frequency of Alveolar Osteitis Following Partially Erupted Mandibular Third Molar Surgery
NA trial testing Concentrated Growth Factor (Test group) in Alveolar Osteitis in 70 participants. Completed in 30 July 2018.
15 July 2018
Quick facts
| Lead sponsor | Ege University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 70 |
| Start date | 2 January 2018 |
| Primary completion | 15 July 2018 |
| Estimated completion | 30 July 2018 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Concentrated Growth Factor (Test group)
- Non-Concentrated Growth Factor (Control group)
Conditions studied
- Alveolar Osteitis — all drugs for Alveolar Osteitis →
- Impacted Tooth — all drugs for Impacted Tooth →
Sponsor
Ege University
Who can join
Adults 18 to 65, any sex, with Alveolar Osteitis or Impacted Tooth. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this prospective study was to assess the effectiveness of concentrated growth factors (CGFs) in preventing the development of alveolar osteitis (AO) after the extraction of partially-erupted mandibular third molars. This study was designed as a randomized controlled clinical trial. In each case, one socket received CGFs and the other served as a control. The predictor variable was the CGFs application and the sides were categorized as 'CGFs' and 'non-CGFs'. The outcome variable was the development of AO during the first postoperative week. Also, demographic variable included age and gender was noted.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of concentrated growth factors on frequency of alveolar Osteitis following partially-erupted mandibular third molar surgery: a randomized controlled clinical study.
Özveri Koyuncu B, Işık G, Özden Yüce M, Günbay S, et al · · 2020 · cited 14× · PMID 32807173 · DOI 10.1186/s12903-020-01210-7
Verify or expand the search:
- PubMed search for NCT04151147
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Alveolar Osteitis
Currently open trials in the same condition.
- NCT06435832 — Evaluations of the Effects of Tranexamic Acid and Chlorhexidine Gel on Alveolar Osteitis Incidence · NA · active not recruiting
Other Ege University trials
Trials by the same sponsor.
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- NCT07344532 — Effect of Preoperative Abdominal Effleurage on Postoperative Constipation · NA · not yet recruiting
- NCT07417748 — Kinesthetic Exercises on Adults · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04151147 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ege University
- Last refreshed: 5 November 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04151147.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing