Who is sponsoring NCT04148807?

NCT04148807 is sponsored by Northeastern University.

What drugs are being tested in NCT04148807?

Interventions in NCT04148807: Progressive Walking with Gait Retraining, Progressive Walking Program.

What condition does NCT04148807 study?

NCT04148807 studies Osteoarthritis, Knee, Knee Pain Chronic.

Is NCT04148807 still recruiting?

NCT04148807 is currently status unknown. Last updated 29 September 2022.

Last reviewed 2022-09-29 · How we verify

NCT04148807

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effectiveness of a Walking Intervention on Impact Loading and Pain

Status unknown NA Last updated 29 September 2022

What this trial tests

NA trial testing Progressive Walking with Gait Retraining in Osteoarthritis, Knee in 40 participants. Status unknown.

Timeline

5 November 2019

Primary endpoint
30 March 2023

30 March 2023

Quick facts

Lead sponsor	Northeastern University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	40
Start date	5 November 2019
Primary completion	30 March 2023
Estimated completion	30 March 2023
Sites	1 location across United States

Drugs / interventions tested

Progressive Walking with Gait Retraining
Progressive Walking Program

Conditions studied

Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →
Knee Pain Chronic — all drugs for Knee Pain Chronic →

Sponsor

Northeastern University

Who can join

45 and older, any sex, with Osteoarthritis, Knee or Knee Pain Chronic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study investigates the feasibility of a gait-retraining program for older adults with knee osteoarthritis. The study will enroll 40 participants, with 20 receiving a gait retraining intervention and 20 receiving a graded walking program without gait retraining.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Reducing knee pain and loading with a gait retraining program for individuals with knee osteoarthritis: Protocol for a randomized feasibility trial.
Corrigan P, Davis IS, James KA, Crossley KM, et al · · 2020 · cited 6× · PMID 36474880 · DOI 10.1016/j.ocarto.2020.100097
Gait Retraining to Reduce Tibial Acceleration Versus a Standard Walking Program for Reducing Knee Pain and Loading in Adults With Knee Osteoarthritis: A Randomized Feasibility Trial.
James KA, Corrigan P, Huang CH, Lanois C, et al · · 2025 · cited 1× · PMID 40728103 · DOI 10.1002/acr2.70079

Verify or expand the search:

Other recruiting trials for Osteoarthritis, Knee

Currently open trials in the same condition.

NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
NCT06488144 — Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans · Phase 3 · recruiting
NCT07386561 — Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty · NA · active not recruiting
NCT07514598 — Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA) · NA · active not recruiting
NCT07058623 — Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement · NA · recruiting

Other Northeastern University trials

Trials by the same sponsor.

NCT07421830 — An Empowering Parent Training Intervention to Increase Physical Activity in Preschool Aged Children With Autism · NA · recruiting
NCT07147894 — Executive Function Training for Children and Adolescents · NA · recruiting
NCT06435819 — ECA-enhanced Document Explanation RCT · NA · recruiting
NCT07139795 — The Mind-Body Project · NA · active not recruiting
NCT06645652 — Visual Arts Interventions With Older Adults · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04148807 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Northeastern University
Last refreshed: 29 September 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04148807.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing