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NCT04144595

Association Between Low Plasma Glucose After Oral Glucose Tolerance Test in Pregnancy With Impaired Fetal Growth

Completed Last updated 13 January 2020
What this trial tests

trial testing 2 hour 75 g Oral glucose tolerance test in Oral Glucose Tolerance Test in 300 participants. Completed in 30 November 2019.

Timeline
1 January 2019
Primary endpoint
28 October 2019
30 November 2019

Quick facts

Lead sponsorHospital Universitario Dr. Jose E. Gonzalez
StatusCompleted
Study typeOBSERVATIONAL
Enrollment300
Start date1 January 2019
Primary completion28 October 2019
Estimated completion30 November 2019
Sites1 location across Mexico

Drugs / interventions tested

Conditions studied

Sponsor

Hospital Universitario Dr. Jose E. Gonzalez

Who can join

Eligibility, female only, with Oral Glucose Tolerance Test or Low Birth Weight. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Objective: To study the association of low maternal plasma glucose in 2 hour 75 g oral glucose tolerance test (OGTT) in women with impaired birth weight and determinate if this result is predictive of low birth weight (\<10th percentile according to the INTERGROWTH-21st newborn weight standards for gestational age/sex). Materials and methods: OGTT at 24-34 week gestation will be performed in pregnant women, the birth weight will be compared between women with low fasting plasma glucose (FPG) (\<10th percentile, \<65 mg/dL) and normal FPG (≥10th percentile, ≥ 65 mg/dL) also for 1 and 2-hour plasma glucose (1-h PG/2-h PG). Receiver operating characteristic curve analysis will be used to determine the optimal lower OGTT threshold for the prediction of low birth weight.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Prediction of low birth weight with hypoglycemia in glucose tolerance test.
    Hernández-Castro F, Berlanga-Garza A, Cruz-Gutiérrez MD, Soria-López JA, et al · · 2021 · cited 2× · PMID 34008784 · DOI 10.11606/s1518-8787.2021055002543

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