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NCT04144322

Short Dental Implants (5 mm) Versus Long Dental Implants (10 mm)

Completed NA Results posted Last updated 6 May 2025
What this trial tests

NA trial testing Zimmer T3 Short Ex Hex With Discrete Crystalline Deposition in Bone Loss, Alveolar in 34 participants. Completed in 22 April 2024.

Timeline
14 October 2019
Primary endpoint
22 April 2024
22 April 2024

Quick facts

Lead sponsorUniversity of Michigan
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposeother
Enrollment34
Start date14 October 2019
Primary completion22 April 2024
Estimated completion22 April 2024
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Michigan

Who can join

Adults 20 to 70, any sex, with Bone Loss, Alveolar. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Change in Mesial-distal (M-D) Bone Loss Primary · Baseline, surgical visit 1 day, 4 months, 5 months, 12 months, 24 months

Comparing mesial-distal (M-D) bone loss between the two groups. This will be measured in millimeters using standardized radiographs of the implant site at the screening visit, surgical visit, 4 months post-op, 5 months post-op, 12 months post-op, and 24 months post-op visits.

Surgery visit
GroupValue95% CI
Short Implant0.63± 0.38
Long Implant0.61± 0.57
4 months (second stage)
GroupValue95% CI
Short Implant-0.41± 0.76
Long Implant-0.40± 1.04
5 months (loading)
GroupValue95% CI
Short Implant-0.55± 0.83
Long Implant-0.64± 0.75
12 months
GroupValue95% CI
Short Implant-0.74± 0.79
Long Implant-0.40± 0.57
24 months
GroupValue95% CI
Short Implant-0.84± 0.62
Long Implant-059± 0.65
Survival Rate Secondary · 5 month post-op, 12 month post-op, and 24 month post-op visits

The survival rate of the two groups will be recorded as a percentage at the 5 month post-op, 12 month post-op, and 24 month post-op visits based on clinician assessment.

5 months (loading)
GroupValue95% CI
Short Implant17
Long Implant15
12 months
GroupValue95% CI
Short Implant17
Long Implant15
24 months
GroupValue95% CI
Short Implant15
Long Implant15
Number of Sites With Bleeding on Probing Secondary · 5 month post-op, 12 month post-op, and 24 month post-op visits

The number of sites with bleeding on probing will be compared between the two groups. Bleeding on probing of the implant site will be measured with a periodontal probe at the 5 month post-op, 12 month post-op, and 24 month post-op visits.

5 months (loading)
GroupValue95% CI
Short Implant.03± .02
Long Implant.08± .05
12 months
GroupValue95% CI
Short Implant.14± .05
Long Implant.39± .09
24 months
GroupValue95% CI
Short Implant.35± .07
Long Implant.32± .08
Probing Pocket Depth Secondary · 5 month post-op, 12 month post-op, and 24 month post-op visits

The probing pocket depths will be compared between the two groups. Probing depths of the implant site will be measured with a periodontal probe at the 5 month post-op, 12 month post-op, and 24 month post-op visits.

5 months (loading)
GroupValue95% CI
Short Implant2.84± 0.15
Long Implant2.94± .15
12 months
GroupValue95% CI
Short Implant3.32± 0.14
Long Implant3.27± .15
24 months
GroupValue95% CI
Short Implant3.79± 0.16
Long Implant3.72± .16

Adverse events — posted to ClinicalTrials.gov

Time frame: Adverse event data was collected during each subject's entire participation in the study (approximately 2 years). Reporting threshold: 5%. Adverse-event reports describe events observed during the trial — not all are caused by the drug.

Short Implant
Serious: 2/17 (12%)
Deaths: 0/17
Long Implant
Serious: 3/17 (18%)
Deaths: 0/17

Serious adverse events (5 terms)

ReactionSystemShort ImplantLong Implant
Vehicle accidentSocial circumstances
AppendicitisGastrointestinal disorders
Coronavirus disease of 2019 and ablationCardiac disorders
AssaultSocial circumstances
Hip replacementMusculoskeletal and connective tissue disorders

Most-reported serious reactions: Vehicle accident, Appendicitis, Coronavirus disease of 2019 and ablation, Assault, Hip replacement.

Data from ClinicalTrials.gov NCT04144322 adverse events section.

Sponsor's own description

The purpose of this study is to evaluate the survival rate of 5 mm short implants compared to longer implants (10 mm) placed in sinus-grafted sites. Primary aim: Compare bone loss between the two groups Secondary aim: Compare surgical time and patient-reported outcomes (satisfaction and post-operative pain)

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Bone Loss, Alveolar

Currently open trials in the same condition.

Other University of Michigan trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04144322.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing