NCT04143256 is a NA clinical trial of JUUL ENDS 5% Virginia Tobacco in Electronic Cigarette Use, sponsored by Juul Labs, Inc..

Who is sponsoring NCT04143256?

NCT04143256 is sponsored by Juul Labs, Inc..

What drugs are being tested in NCT04143256?

Interventions in NCT04143256: JUUL ENDS 5% Virginia Tobacco, JUUL 3% Virginia Tobacco ENDS, JUUL 5% Mint ENDS, JUUL 3% Mint ENDS, JUUL 5% Menthol ENDS, JUUL 3% Menthol ENDS, JUUL 5% Mango ENDS, JUUL 3% Mango ENDS, US Cigarette, Non-menthol - Marlboro Gold King Size, US Cigarette, Menthol - Newport King Size.

What condition does NCT04143256 study?

NCT04143256 studies Electronic Cigarette Use, Cigarette Use, Electronic, Tobacco Use, Tobacco Smoking.

Is NCT04143256 still recruiting?

NCT04143256 is currently completed. Last updated 11 February 2020.

Last reviewed 2020-02-11 · How we verify

NCT04143256

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluating Selected Constituents in the Exhaled Breath Samples

Completed NA Last updated 11 February 2020

What this trial tests

NA trial testing JUUL ENDS 5% Virginia Tobacco in Electronic Cigarette Use in 135 participants. Completed in 13 December 2019.

Timeline

3 October 2019

Primary endpoint
12 December 2019

13 December 2019

Quick facts

Lead sponsor	Juul Labs, Inc.
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	other
Enrollment	135
Start date	3 October 2019
Primary completion	12 December 2019
Estimated completion	13 December 2019
Sites	3 locations across United States

Drugs / interventions tested

JUUL ENDS 5% Virginia Tobacco
JUUL 3% Virginia Tobacco ENDS
JUUL 5% Mint ENDS
JUUL 3% Mint ENDS
JUUL 5% Menthol ENDS
JUUL 3% Menthol ENDS
JUUL 5% Mango ENDS
JUUL 3% Mango ENDS
US Cigarette, Non-menthol - Marlboro Gold King Size
US Cigarette, Menthol - Newport King Size

Conditions studied

Electronic Cigarette Use — all drugs for Electronic Cigarette Use →
Cigarette Use, Electronic — all drugs for Cigarette Use, Electronic →
Tobacco Use — all drugs for Tobacco Use →
Tobacco Smoking — all drugs for Tobacco Smoking →

Sponsor

Juul Labs, Inc.

Who can join

Adults 21 to 65, any sex, with Electronic Cigarette Use or Cigarette Use, Electronic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

An Open-Label, Multi-Center Study to Evaluate Selected Constituents in the Exhaled Breath Samples From the Use of JUUL Nicotine Salt Pod System Product (5% and 3% Virginia Tobacco, Mint, Mango, Menthol) Users and Conventional Cigarettes (Non-Menthol and Menthol Flavors)

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Prediction of potential passive exposure from commercial electronic nicotine delivery systems using exhaled breath analysis and computational fluid dynamic techniques.
Oldham MJ, Bailey PC, Castro N, Lang Q, et al · · 2021 · cited 5× · PMID 34544050 · DOI 10.1088/1752-7163/ac2884

Verify or expand the search:

Other recruiting trials for Electronic Cigarette Use

Currently open trials in the same condition.

NCT06609109 — Effect of Cannabis on E-Cigarette Use Behavior · Phase 1 · recruiting
NCT06610838 — Effects of E-cigarette Use on Health · recruiting
NCT04907136 — Developing and Testing Health Warning Labels on the ENDS Device · NA · recruiting
NCT06142877 — Effects of Social Media Use on Young Adults' E-Cigarette Use · NA · recruiting
NCT05338801 — Effect of Menthol on ENDS Users' Addiction and Exposure · NA · recruiting

Other Juul Labs, Inc. trials

Trials by the same sponsor.

NCT04088175 — Study to Characterize Puffing Topography With Use of JUUL Electronic Nicotine Delivery Systems (ENDS) in Adult, Closed-S · NA · completed
NCT04123041 — Characterize the Nicotine Uptake and Subjective Effects With Use of JUUL Electronic Nicotine Delivery Systems · NA · completed
NCT04107779 — Changes in Biomarkers of Cigarette Smoke Exposure After Switching Either Exclusively or Partly to JUUL ENDS · NA · completed
NCT03700112 — Clinical Study Comparing 7 ENDS Products and 1 Combustible Cigarette Using 2 Delivery Methods. · NA · completed
NCT03719391 — United States Pre-Market Tobacco Application Pharmacokinetics · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04143256 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Juul Labs, Inc.
Last refreshed: 11 February 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04143256.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing