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NCT04142827: BX
The Effect of Long Term Therapy With High Flow Humidification Compared to Usual Care in Patients With Bronchiectasis (BX)
NA trial testing High Flow Humidification in Bronchiectasis Adult in 160 participants. Status unknown.
3 March 2020
Quick facts
| Lead sponsor | Dr. Giuseppe Fiorentino |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 160 |
| Start date | 4 September 2019 |
| Primary completion | 3 March 2020 |
| Estimated completion | 3 September 2020 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- High Flow Humidification
Conditions studied
- Bronchiectasis Adult — all drugs for Bronchiectasis Adult →
- Lung Infection — all drugs for Lung Infection →
- Quality of Life — all drugs for Quality of Life →
- Humidifier Lung — all drugs for Humidifier Lung →
Sponsor
Dr. Giuseppe Fiorentino
Who can join
Eligibility, any sex, with Bronchiectasis Adult or Lung Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study is intended to understand the benefit of Long Term Home care Therapy with nasal High flow in Bronchiectasis patients at home. Primary end point is to evaluate daily life compared to usual care and secondary is to evaluate the changes in lung function
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Danish respiratory society guideline for long-term high flow nasal cannula treatment, with or without supplementary oxygen.
Weinreich UM, Juhl KS, Søby Christophersen M, Gundestrup S, et al · · 2023 · cited 16× · PMID 36861118 · DOI 10.1080/20018525.2023.2178600
Verify or expand the search:
- PubMed search for NCT04142827
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Bronchiectasis Adult
Currently open trials in the same condition.
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- NCT06900062 — The C-BRIDGE Study: China Bronchiectasis Research Involving Databases, Genomics, and Endotyping · recruiting
- NCT06820918 — Physiotherapy With Positive Expiratory Pressure (PEP) Bottle in Patients With Bronchiectasis · NA · active not recruiting
- NCT06801327 — Comparison Between Conventional Respiratory Physiotherapy and the Simeox Device in Patients With Bronchiectasis · NA · recruiting
- NCT06760273 — Long-term Impact of Inhaled Tobramycin for Pseudomonas Aeruginosa Eradication in Bronchiectasis (ERASE II) · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04142827 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dr. Giuseppe Fiorentino
- Last refreshed: 29 October 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04142827.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing