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NCT04138030
Conventional Endoscopic Mucosal Resection Versus Cold Snare Endoscopic Mucosal Resection of Colonic Lateral Spreading Lesions - A Randomised Controlled Trial
NA trial testing Conventional Endoscopic Mucosal Resection in Adenoma Colon in 182 participants. Completed in 5 March 2024.
5 March 2024
Quick facts
| Lead sponsor | Western Sydney Local Health District |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 182 |
| Start date | 12 November 2019 |
| Primary completion | 5 March 2024 |
| Estimated completion | 5 March 2024 |
| Sites | 1 location across Australia |
Drugs / interventions tested
- Conventional Endoscopic Mucosal Resection
- Cold Snare Endoscopic Mucosal Resection
Conditions studied
- Adenoma Colon — all drugs for Adenoma Colon →
- Colon Adenoma — all drugs for Colon Adenoma →
- Colon Cancer — all drugs for Colon Cancer →
Sponsor
Western Sydney Local Health District — full company profile →
Who can join
Adults 18 to 99, any sex, with Adenoma Colon or Colon Adenoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Comparing the complete resection rate and subsequent adenoma recurrence rate at surveillance colonoscopy of 15-40mm laterally spreading adenomas for conventional EMR vs. cold snare EMR.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Cold versus hot snare endoscopic mucosal resection for large (≥15 mm) flat non-pedunculated colorectal polyps: a randomised controlled trial.
O'Sullivan T, Cronin O, van Hattem WA, Mandarino FV, et al · · 2024 · cited 30× · PMID 38964854 · DOI 10.1136/gutjnl-2024-332807 -
Endoscopic Management of Large Non-Pedunculated Colorectal Polyps.
Cronin O, Bourke MJ. · · 2023 · cited 8× · PMID 37568621 · DOI 10.3390/cancers15153805
Verify or expand the search:
- PubMed search for NCT04138030
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Conventional Endoscopic Mucosal Resection
Trials testing the same drug.
- NCT03021135 — Conventional Endoscopic Mucosal Resection vs Underwater Resection for Colorectal Non-pedunculated Colorectal Lesions · NA · completed
Other recruiting trials for Adenoma Colon
Currently open trials in the same condition.
- NCT07153458 — Identification of New Non-invasive, Predictive, and Diagnostic Biomarkers for Colorectal Cancer · recruiting
- NCT07033156 — An Exploratory Study on Gene Methylation Detection of Colorectal Cancer · recruiting
- NCT07450612 — Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection · recruiting
- NCT06073561 — Underwater Endoscopic Mucosal Resection · NA · recruiting
- NCT04756453 — The Effect of Clip-traction on ESD Resection Time. · NA · recruiting
Other Western Sydney Local Health District trials
Trials by the same sponsor.
- NCT07445334 — Catheter Ablation Versus Anti-arrhythmic Drugs for Premature Ventricular Complexes · NA · not yet recruiting
- NCT06360939 — Radiotherapy vs Catheter Ablation for Ventricular Tachycardia in Structural Heart Disease · NA · recruiting
- NCT06365411 — GEnomic Medicine in Kidney Transplantation Study · not yet recruiting
- NCT06828562 — GENomic Predictors in A Multi-Ethnic Population With Kidney Disease Study · enrolling by invitation
- NCT05509153 — A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04138030 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Western Sydney Local Health District
- Last refreshed: 27 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04138030.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing