Last reviewed · How we verify
NCT04137913: CHROMA
Cognitive Health Research on Musical Arts
NA trial testing Musical arts intervention in Cognitive Impairment in 81 participants. Completed in 15 June 2023.
10 November 2022
Quick facts
| Lead sponsor | William Marsh Rice University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 81 |
| Start date | 19 November 2019 |
| Primary completion | 10 November 2022 |
| Estimated completion | 15 June 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Musical arts intervention
Conditions studied
- Cognitive Impairment — all drugs for Cognitive Impairment →
- Creativity — all drugs for Creativity →
Sponsor
William Marsh Rice University
Who can join
Adults 18 to 90, any sex, with Cognitive Impairment or Creativity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is designed to assess the therapeutic effect that music creativity engagement has on cognition and social/emotional well-being, with a special interest in quantifying the associated connectivity changes in the brain. Investigators will measure the effect that a creative music intervention has on health-related outcomes for mild cognitive impairment (MCI) patients using novel neural markers, laboratory-based cognitive tasks, assessments of loneliness, perceptions of stress, and social support.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Feasibility and acceptability of a group music creativity intervention for adults with varying cognitive function.
Wu-Chung EL, Brandt AK, Bonomo ME, Denny BT, et al · · 2024 · cited 1× · PMID 39238932 · DOI 10.1080/10400419.2023.2272105 -
Music-induced cognitive change and whole-brain network flexibility: a pilot study.
Wu-Chung EL, Bonomo ME, Brandt AK, Denny BT, et al · · 2025 · PMID 40538861 · DOI 10.3389/fnins.2025.1567605
Verify or expand the search:
- PubMed search for NCT04137913
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Cognitive Impairment
Currently open trials in the same condition.
- NCT07504276 — Tele-Rehabilitation vs Conventional Rehabilitation for Cognitive Improvement in Stroke Survivors. · NA · recruiting
- NCT07396779 — Cognitive Task-Based Walking Effects on Cognition, Mood, Sleep, and Quality of Life in Older Adults With Brain Fog · NA · active not recruiting
- NCT07084831 — A Study Evaluating the Efficacy of Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of Treatment i · Phase 3 · recruiting
- NCT07125378 — Living Independence Through Functional Training · Phase 1, PHASE2 · recruiting
- NCT07268079 — Validation of the VIRADIA App for Neurological and Cognitive Diagnostics in Virtual Reality · recruiting
Other William Marsh Rice University trials
Trials by the same sponsor.
- NCT07554417 — Combatting Muscle Loss in Obese Adult Patients on GLP-1 Medications Through Dietary Counseling and Exercise During Treat · Phase 4 · not yet recruiting
- NCT06003140 — Efficacy of Celsi Warmer for the Management of Hypothermic Newborns at the Lagos University Teaching Hospital in Lagos, · NA · recruiting
- NCT06000826 — Efficacy of Celsi Warmer for the Management of Hypothermic Newborns · NA · unknown
- NCT05876884 — Efficacy of a Low-cost Warming Mattress Celsi Warmer for the Management of Hypothermic Newborns at Muhimbili National Ho · NA · unknown
- NCT04905381 — Can the Language Environment Analysis Start Program Improve Children's Readiness for School? LENA Program Evaluation · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04137913 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by William Marsh Rice University
- Last refreshed: 25 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04137913.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing