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NCT04137393

The Effect of Brushing With Salvadorapersica (Miswak) Sticks on Salivary Streptococcus Mutants and Plaque Level in Children: A Clinical Trial

Completed Phase 3 Last updated 22 October 2019
What this trial tests

Phase 3 trial testing brushing in Plaque, Dental in 70 participants. Completed in 1 June 2018.

Timeline
1 October 2016
Primary endpoint
1 October 2017
1 June 2018

Quick facts

Lead sponsorHeba sabbagh
PhasePhase 3
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposeprevention
Enrollment70
Start date1 October 2016
Primary completion1 October 2017
Estimated completion1 June 2018

Drugs / interventions tested

Conditions studied

Sponsor

Heba sabbagh

Who can join

Adults 8 to 9, male only, with Plaque, Dental. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Sponsor's own description

Objectives: to evaluate the effect of brushing with Salvadora persica (Miswak) on streptococcus mutants compared to brushing with fluoridated tooth paste (FTP) in children. Methods: A total of 94 healthy children (8 years old) from an elementary governmental school in Jeddah, Saudi Arabia were grouped to Miswak and FTP groups. They were assessed for their salivary level of mutans streptococci species, and lactobacillus at the baseline and three weeks after brushing. Caries level using DMFT/dmft, and plaque amount using Greene Vermillion simplified oral hygiene index were recorded.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. The effect of brushing with Salvadora persica (miswak) sticks on salivary Streptococcus mutans and plaque levels in children: a clinical trial.
    Sabbagh HJ, AlGhamdi KS, Mujalled HT, Bagher SM. · · 2020 · cited 11× · PMID 32054468 · DOI 10.1186/s12906-020-2847-3

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