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NCT04135235
Effect and Safety of Propofol Fumarate for Mother-to-child Blocking of Hepatitis B
trial testing TAF in Chronic Hepatitis B Infection in 440 participants. Status unknown.
1 August 2021
Quick facts
| Lead sponsor | Beijing Ditan Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 440 |
| Start date | 1 August 2019 |
| Primary completion | 1 August 2021 |
| Estimated completion | 1 August 2021 |
| Sites | 1 location across China |
Drugs / interventions tested
- TAF — full drug profile →
- TDF
Conditions studied
- Chronic Hepatitis B Infection — all drugs for Chronic Hepatitis B Infection →
- High Viral Load — all drugs for High Viral Load →
Sponsor
Beijing Ditan Hospital
Who can join
Adults 18 to 35, female only, with Chronic Hepatitis B Infection or High Viral Load. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is a prospective study. The subject will select 440 cases of pregnant women with high hepatitis B virus load, and one group will take maternal and child blockade treatment with propofol fumarate. One group will take tenofovir disoproxil fumarate. Broken treatment, compare the failure rate of maternal and child blockade and the incidence of maternal and child adverse events in the two groups, and explore the efficacy and safety of propofol flavuril for the treatment of hepatitis B mother-infant block.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04135235
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of TAF
Trials testing the same drug.
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- NCT05861674 — A Study to Assess Efficacy and Safety of HH-003 Injection in Subjects With Chronic Hepatitis Delta Virus Infection · Phase 2 · completed
- NCT05123599 — A Study of JNJ-73763989, JNJ-64300535, and Nucleos(t)Ide Analogs in Virologically Suppressed, Hepatitis B e Antigen (HBe · Phase 1 · completed
- NCT05005507 — A Study of JNJ-73763989, Pegylated Interferon Alpha-2a and Nucleos(t)Ide Analogs in Participants With Chronic Hepatitis · Phase 2 · terminated
- NCT04551261 — GLS4/RTV and TAF Drug-drug Interaction · Phase 1 · completed
Other recruiting trials for Chronic Hepatitis B Infection
Currently open trials in the same condition.
- NCT07342881 — Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Part · Phase 1 · recruiting
Other Beijing Ditan Hospital trials
Trials by the same sponsor.
- NCT06642740 — Study on the Efficacy and Safety of Avatricopal in Patients With CLD Complicated With Thrombocytopenia · enrolling by invitation
- NCT06777173 — Clinical Study of Antiviral Therapy Combined With Novel Immunotherapy for CHB in Adults · NA · enrolling by invitation
- NCT05929963 — Observational Study of the Interaction Between Hepatitis C Virus Infection and Pregnancy · unknown
- NCT05812612 — UDCA in the Treatment of COVID-19 Infection and Its Clinical Prognosis in Patients With Autoimmune Liver Disease · unknown
- NCT05765279 — A Study to Assess the Efficacy of HH-120 Nasal Spray for Prevention of SARS-CoV-2 Infection in Adult Close Contacts of I · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04135235 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Beijing Ditan Hospital
- Last refreshed: 22 October 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04135235.
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