NCT04134624

EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic Shock

Terminated NA Last updated 22 September 2021

What this trial tests

NA trial testing Sepsis care bundle in Sepsis in 215 participants. Terminated before completion.

Timeline

11 September 2019

Primary endpoint
27 February 2020

8 July 2021

Quick facts

Lead sponsor	HealthPartners Institute
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	non randomized
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	215
Start date	11 September 2019
Primary completion	27 February 2020
Estimated completion	8 July 2021
Sites	1 location across United States

Drugs / interventions tested

• Sepsis care bundle

Conditions studied

• Sepsis — all drugs for Sepsis →
• Sepsis, Severe — all drugs for Sepsis, Severe →
• Septic Shock — all drugs for Septic Shock →

Sponsor

HealthPartners Institute

Who can join

Adults 18 to 100, any sex, with Sepsis or Sepsis, Severe. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is designed to improve the outcomes for patients suffering from severe sepsis and septic shock (SS/SS) by decreasing the time from first medical contact to antibiotic administration. This is a stepwise study that aims to demonstrate the ability of paramedics to accurately obtain blood cultures prior to hospital arrival, administer a broad spectrum antibiotic and initiate IV fluid resuscitation in patients meeting predefined criteria for SS/SS.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.