NCT04134403 (STASIS) is a Phase 3 clinical trial of STASIS in Septic Shock, sponsored by Baqiyatallah Medical Sciences University.

Who is sponsoring NCT04134403?

NCT04134403 is sponsored by Baqiyatallah Medical Sciences University.

What drugs are being tested in NCT04134403?

Interventions in NCT04134403: STASIS.

What condition does NCT04134403 study?

NCT04134403 studies Septic Shock.

Is NCT04134403 still recruiting?

NCT04134403 is currently status unknown. Last updated 22 October 2019.

Last reviewed 2019-10-22 · How we verify

NCT04134403: STASIS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Steroids, Thiamine and Ascorbic Acid in Septic Shock

Status unknown Phase 3 Last updated 22 October 2019

What this trial tests

Phase 3 trial testing STASIS in Septic Shock in 80 participants. Status unknown.

Timeline

1 December 2019

Primary endpoint
1 November 2020

1 December 2020

Quick facts

Lead sponsor	Baqiyatallah Medical Sciences University
Phase	Phase 3
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	80
Start date	1 December 2019
Primary completion	1 November 2020
Estimated completion	1 December 2020

Drugs / interventions tested

STASIS — full drug profile →

Conditions studied

Septic Shock — all drugs for Septic Shock →

Sponsor

Baqiyatallah Medical Sciences University

Who can join

18 and older, any sex, with Septic Shock. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of this project is to determine if in patients admitted to the hospital with septic shock (population), does treatment with a bundle including hydrocortisone, thiamine, and ascorbic acid improve in-hospital or 28-day mortality (primary outcomes) or surrogate markers of illness severity including: (1) ICU or hospital length-of-stay, (2) duration of invasive mechanical ventilation, (3) duration of vasopressor administration, (4) incidence and severity of ICU delirium, and (5) illness severity (secondary outcomes).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Corticosteroids for treating sepsis in children and adults.
Annane D, Briegel J, Granton D, Bellissant E, et al · · 2025 · cited 7× · PMID 40470636 · DOI 10.1002/14651858.cd002243.pub5

Verify or expand the search:

Other recruiting trials for Septic Shock

Currently open trials in the same condition.

NCT07179276 — Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock · NA · recruiting
NCT07383103 — Hydrocortisone and Fludrocortisone for the Treatment of Septic Shock · Phase 4 · recruiting
NCT07419802 — OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) Study · recruiting
NCT07264543 — Early Methylene Blue in the Microhemodynamics of Septic Patients · Phase 2, PHASE3 · recruiting
NCT04855786 — External Drainage of Thoracic Duct Lymph to Reduce Inflammatory Cytokines in Septic Shock Patients · NA · recruiting

Other Baqiyatallah Medical Sciences University trials

Trials by the same sponsor.

NCT06369688 — IDEAL SKIIN CARES Bundle to Prevent Pressure Injury · NA · not yet recruiting
NCT04463420 — Safety and Efficacy of PHR 160 Spray on the Outcomes of Patients With COVID-19 · NA · unknown
NCT04466280 — Efficacy and Safety of Mucoadhesive Sustained Release, Mucodentol, in Comparison With Hydroxychloroquine to Prevent COVI · NA · withdrawn
NCT04460092 — Using 32 - Gauge Needles With Lengths of 5 mm and 8 mm on Pain Post-injection, Leak and Blood Glucose · NA · unknown
NCT04376814 — Favipiravir Plus Hydroxychloroquine and Lopinavir/Ritonavir Plus Hydroxychloroquine in COVID-19 · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04134403 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Baqiyatallah Medical Sciences University
Last refreshed: 22 October 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04134403.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing