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NCT04131049

Comparison of Two Different Insulin Dose Calculation Algorithms in Type 1 Diabetes

Completed NA Last updated 9 February 2021
What this trial tests

NA trial testing High GI calculated by CC (CHGI) in Insulin-Dependent Diabetes Mellitus 1 in 15 participants. Completed in 24 January 2020.

Timeline
24 June 2019
Primary endpoint
24 November 2019
24 January 2020

Quick facts

Lead sponsorTC Erciyes University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designcrossover
Maskingsingle
Primary purposescreening
Enrollment15
Start date24 June 2019
Primary completion24 November 2019
Estimated completion24 January 2020
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

TC Erciyes University

Who can join

Adults 14 to 18, any sex, with Insulin-Dependent Diabetes Mellitus 1. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to compare the impact of carbohydrate counting (CC) method which is standard insulin dose calculation algorithm and food insulin index (FII) method which is a new algorithm on postprandial glucose following a high fat and a high protein meal in adolescent with type 1 diabetes. A randomized, single-blind and crossover trial included 14 adolescents aged 14-18 years with type 1 diabetes. All participants were sent to their homes for 4 consecutive days with a different glycemic index breakfast. The insulin doses of the meals were calculated according to CC and FII methods. Test breakfasts with different GIs and insulin requirements calculated with different algorithms are as follows: High GI calculated by CC (CHGI), low GI calculated by CC (CLGI), high GI calculated by FII (FHGI) and low GI calculated by FII (FLGI).

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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