NCT04129333 (HYPIC) is a NA clinical trial of Hypnosis in Invasive Procedure, sponsored by Rennes University Hospital.

Who is sponsoring NCT04129333?

NCT04129333 is sponsored by Rennes University Hospital.

What drugs are being tested in NCT04129333?

Interventions in NCT04129333: Hypnosis, No hypnosis.

What condition does NCT04129333 study?

NCT04129333 studies Invasive Procedure.

Is NCT04129333 still recruiting?

NCT04129333 is currently completed. Last updated 9 November 2022.

Last reviewed 2022-11-09 · How we verify

NCT04129333: HYPIC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

HYPIC Hypnosis for Procedural Pain in the Intensive Care Unit

Completed NA Last updated 9 November 2022

What this trial tests

NA trial testing Hypnosis in Invasive Procedure in 80 participants. Completed in 11 October 2022.

Timeline

30 December 2019

Primary endpoint
25 January 2022

11 October 2022

Quick facts

Lead sponsor	Rennes University Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	supportive care
Enrollment	80
Start date	30 December 2019
Primary completion	25 January 2022
Estimated completion	11 October 2022
Sites	2 locations across France

Drugs / interventions tested

Hypnosis
No hypnosis

Conditions studied

Invasive Procedure — all drugs for Invasive Procedure →

Sponsor

Rennes University Hospital

Who can join

18 and older, any sex, with Invasive Procedure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Procedural pain in resuscitation is common in the conscious patient. However, analgesia and sedation may be impossible because of the acute pathology leading to resuscitation, comorbidities or the urgency of the invasive procedure. In addition, the use of analgesics and sedatives is responsible for adverse effects. In this context, hypnosis appears to be an additional analgesic tool that would reduce the consumption of analgesics and sedatives and thus reduce their side effects.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Hypnosis for unplanned procedural pain in the intensive care unit: the HYPIC randomized clinical trial.
Maamar A, Faleur C, Pedrono K, Adeux MP, et al · · 2025 · PMID 40682163 · DOI 10.1186/s13054-025-05563-9

Verify or expand the search:

Other trials of Hypnosis

Trials testing the same drug.

NCT07518498 — Hypnosis During Mechanical Ventilation Weaning · NA · not yet recruiting
NCT07254299 — Hypnosis to Improve Well-beings of Critically Ill Patients and Prevent Post-intensive Care Syndrome · NA · not yet recruiting
NCT07386392 — Effect of Hypnosis and Virtual Reality on Anxiety During Treatment for Acute Myeloid Leukemia · NA · not yet recruiting
NCT07256704 — Hypnosis and Attention in Patients With a Neurological Disease (Stroke, Traumatic Brain Injury and Multiple Sclerosis) · NA · recruiting
NCT07173348 — Hypnosis on Breathlessness Mastery in Patients With Persistent Dyspnea · NA · not yet recruiting

Other Rennes University Hospital trials

Trials by the same sponsor.

NCT07527949 — PASTRAMI : Patient-specific Statistics for Microstructure-augmented Connectomics · NA · not yet recruiting
NCT07449832 — Sperm Epigenome in Hodgkin Lymphoma · NA · not yet recruiting
NCT06950398 — Normothermic Oxygenated Perfusion (NMP) Viability Testing Before Transplantation of Discarded Livers · Phase 2 · not yet recruiting
NCT07188753 — Randomized Controlled Trial Testing the Efficacy of Transcranial Magnetic Stimulation by Accelerated & High-dose Theta-b · NA · not yet recruiting
NCT06898099 — Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR) · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04129333 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Rennes University Hospital
Last refreshed: 9 November 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04129333.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing