NCT04125446 (GE-CIP) is a clinical trial in Cancer, sponsored by University Hospital, Gasthuisberg.

Who is sponsoring NCT04125446?

NCT04125446 is sponsored by University Hospital, Gasthuisberg.

What condition does NCT04125446 study?

NCT04125446 studies Cancer, Pregnancy.

Is NCT04125446 still recruiting?

NCT04125446 is currently status unknown. Last updated 27 September 2022.

Last reviewed 2022-09-27 · How we verify

NCT04125446: GE-CIP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Genomic and Epigenomic Alterations After Cancer Treatment in Pregnancy

Status unknown Last updated 27 September 2022

What this trial tests

trial in Cancer in 150 participants. Status unknown.

Timeline

15 October 2019

Primary endpoint
31 December 2023

31 December 2023

Quick facts

Lead sponsor	University Hospital, Gasthuisberg
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	150
Start date	15 October 2019
Primary completion	31 December 2023
Estimated completion	31 December 2023
Sites	1 location across Belgium

Conditions studied

Cancer — all drugs for Cancer →
Pregnancy — all drugs for Pregnancy →

Sponsor

University Hospital, Gasthuisberg

Who can join

Eligibility, any sex, with Cancer or Pregnancy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators want to obtain a fundamental understanding if and which chemotherapeutic agents used for treating cancer during pregnancy are associated with placental and/or offspring (epi)genetic changes, potentially causing FGR and childhood/adult diseases later in life.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells.
Struys I, Velázquez C, Ubels J, LeJeune CL, et al · · 2025 · cited 1× · PMID 39852764 · DOI 10.1158/2159-8290.cd-24-1368

Verify or expand the search:

Other recruiting trials for Cancer

Currently open trials in the same condition.

NCT07390045 — Exercise and Cognitive Rehabilitation Interventions for Older Cancer Survivors · NA · recruiting
NCT07528547 — Hypersight and Ethos In Pediatric Radiotherapy · NA · recruiting
NCT07481890 — Feasibility and Efficacy of the EMDR Toolbox Method in Cancer Patients. · NA · recruiting
NCT07402057 — Implementation and Evaluation of a Program Aimed at Facilitating Palliative Care Conversations · NA · recruiting
NCT07305740 — On-Trac: An Online Intervention for Cancer Survivors Managing Anxiety · NA · recruiting

Other University Hospital, Gasthuisberg trials

Trials by the same sponsor.

NCT06354738 — Improving Endometrial Cancer Assessment by Combining Genomic Profiling and Surgical Assessment · NA · recruiting
NCT04904263 — Advisory Board on Cancer, Infertility and Pregnancy · unknown
NCT03676478 — Assessing Timing of Enteral Feeding Support in Esophageal Cancer Patients on Muscle functTion and Survival · NA · terminated

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04125446 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital, Gasthuisberg
Last refreshed: 27 September 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04125446.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing