NCT04120480 is a NA clinical trial of Pharmacogenomic test in Polypharmacy, sponsored by Kaiser Permanente.

Who is sponsoring NCT04120480?

NCT04120480 is sponsored by Kaiser Permanente.

What drugs are being tested in NCT04120480?

Interventions in NCT04120480: Pharmacogenomic test.

What condition does NCT04120480 study?

NCT04120480 studies Polypharmacy.

Is NCT04120480 still recruiting?

NCT04120480 is currently active, enrolled. Last updated 2 August 2024.

Last reviewed 2024-08-02 · How we verify

NCT04120480

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effectiveness of PGx Testing

Active, enrolled NA Last updated 2 August 2024

What this trial tests

NA trial testing Pharmacogenomic test in Polypharmacy in 600 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

15 November 2019

Primary endpoint
30 June 2026

31 December 2027

Quick facts

Lead sponsor	Kaiser Permanente
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	600
Start date	15 November 2019
Primary completion	30 June 2026
Estimated completion	31 December 2027
Sites	1 location across United States

Drugs / interventions tested

Pharmacogenomic test

Conditions studied

Polypharmacy — all drugs for Polypharmacy →

Sponsor

Kaiser Permanente — full company profile →

Who can join

Adults 18 to 79, any sex, with Polypharmacy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine the clinical and economic effectiveness of a pharmacogenomic (PGx) approach to prescribing medications in patients with high-risk polypharmacy in an integrated healthcare delivery system. Investigators hypothesize that patients who receive the RightMed® PGx test from OneOme, LLC with subsequent counseling of their prescribers by a study pharmacist, as needed, on the appropriateness of their prescribed medications will experience lower one-year follow-up healthcare utilization and expenditures compared to control patients who receive usual care.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Pharmacogenetic interventions to improve outcomes in patients with multimorbidity or prescribed polypharmacy: a systematic review.
O'Shea J, Ledwidge M, Gallagher J, Keenan C, et al · · 2022 · cited 18× · PMID 35194175 · DOI 10.1038/s41397-021-00260-6

Verify or expand the search:

Other recruiting trials for Polypharmacy

Currently open trials in the same condition.

NCT06110156 — Population Health Approach to Optimizing Medications in Older Adults · NA · active not recruiting
NCT07022990 — Improving Medication Management in World Trade Center Responders · NA · recruiting
NCT06451692 — Prioritising Patient Medication Review: Hospitals Reaching Out · NA · recruiting
NCT05526963 — Reduction of Polypharmacy in Elderly People With Multiple Diseases · NA · recruiting
NCT06273761 — Evaluation of Medication Management Service · NA · recruiting

Other Kaiser Permanente trials

Trials by the same sponsor.

NCT07522645 — Adherence to Dyslipidemia Therapy: Harnessing Evidence From Randomized Evaluations in AtheroSclerotic CardioVascular Dis · NA · not yet recruiting
NCT07474038 — AI-Supported Cognitive Rehabilitation for Older Adults With Mild Cognitive Impairment · NA · enrolling by invitation
NCT07467668 — Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure · NA · not yet recruiting
NCT07216859 — Screening Cardiometabolic Opportunities Using Transformative Echocardiography Artificial Intelligence (SCOUT Echo-AI) · NA · not yet recruiting
NCT07264062 — MetSense Pilot and Feasibility · NA · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04120480 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Kaiser Permanente
Last refreshed: 2 August 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04120480.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing