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NCT04118400
Ventilator Weaning Outcome Between NIV-NAVA and Nasal CPAP (or IMV ) Modes in Premature Neonates
trial testing NIV-NAVA in Respiratory Distress Syndrome in Premature Infant in 60 participants. Status unknown.
6 October 2020
Quick facts
| Lead sponsor | Taipei Medical University Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 31 October 2019 |
| Primary completion | 6 October 2020 |
| Estimated completion | 31 August 2021 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- NIV-NAVA
- Nasal CPAP or NIMV mode
Conditions studied
- Respiratory Distress Syndrome in Premature Infant — all drugs for Respiratory Distress Syndrome in Premature Infant →
Sponsor
Taipei Medical University Hospital
Who can join
Adults 30 Weeks to 37 Weeks, any sex, with Respiratory Distress Syndrome in Premature Infant. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Premature neonates are prone to respiratory distress and need ventilator support because of the rapid breathing and large variations in respiratory patterns. The setting and adjustment of the ventilator for premature neonate is not easy, often resulting in poor patient-ventilator interaction, increased work of breathing, patient discomfort and delayed weaning . Recently, a new ventilation mode (NAVA; Neurally Adjusted Ventilatory Assist) mode, allows the respirator to provide a proportional ventilation mode based on the patients' diaphragm electrical activity, which was validated in many domestic and international clinical researches. The NAVA mode improves patient-ventilator interaction, reduces work of breathing and contributes to early weaning and extubation . When participating in this study, the neonate with receive a special oral tube placement, which is used to replace the original gastric tube to monitor the electrical activity of the diaphragm.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04118400
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Related trials
Other trials of NIV-NAVA
Trials testing the same drug.
- NCT05446272 — The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial · NA · recruiting
- NCT02590757 — Comparison of NIV-NAVA vs. N-CPAP After Extubation in Preterm Infants Study · NA · completed
Other recruiting trials for Respiratory Distress Syndrome in Premature Infant
Currently open trials in the same condition.
- NCT07344714 — Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting · recruiting
- NCT07098910 — Surfactant Therapy Via Supraglottic Airway to Preterm Neonates With RDS in Vietnam · NA · recruiting
- NCT06554522 — Pragmatic Evaluation of Respiratory Distress Syndrome Treatment in Africa · Phase 4 · recruiting
- NCT06557551 — Prophylactic Surfactant by Thin Endotracheal Catheter for Preterm Infants At Birth: the ProTeCt Trial · NA · recruiting
- NCT06642285 — Effect of Implementing Evidence Based Practices on Prevention of Associated Nasal Pressure Injuries Among Preterm Neonat · NA · recruiting
Other Taipei Medical University Hospital trials
Trials by the same sponsor.
- NCT07294469 — Menthol for Improving Movement and Sleep in Parkinson's Disease Patients · Phase 2 · not yet recruiting
- NCT07114289 — Spontaneous Breathing Trials Using Pressure Support or T-Piece in Overweight and Obese Patients · NA · recruiting
- NCT06949618 — Repetitive Transcranial Magnetic Stimulation in Cancer Pain Management · NA · not yet recruiting
- NCT05830578 — Clinical Validation of the Electrocardiogram Measurement · unknown
- NCT05877079 — TRPM8 in Acute Ischemic Stroke by Topical Menthol · Phase 2 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04118400 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Taipei Medical University Hospital
- Last refreshed: 12 March 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04118400.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing