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NCT04117334
Determining Best Indications for Bracing for Adolescent Idiopathic Scoliosis
trial testing Bracing in Adolescent Idiopathic Scoliosis in 700 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | The University of Hong Kong |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 700 |
| Start date | 1 December 2016 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 March 2026 |
| Sites | 2 locations across Hong Kong |
Drugs / interventions tested
- Bracing
Conditions studied
- Adolescent Idiopathic Scoliosis — all drugs for Adolescent Idiopathic Scoliosis →
Sponsor
The University of Hong Kong
Who can join
Adults 10 to 18, any sex, with Adolescent Idiopathic Scoliosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a prospective study for Investigating the cost-effectiveness of current bracing protocols for adolescent idiopathic scoliosis (AIS). It is hypothesized that aggressive management of adolescent idiopathic scoliosis (AIS) including early bracing at mild curve magnitudes and surgery at 40 degrees is more cost-effective while maintaining similar health quality of life. Scoliosis Research Society 22-item and EuroQol- 5 dimension questionnaires and direct/indirect medical costs will be utilized for the cost-effectiveness analysis and health related quality of life assessment. The findings of this study have the potential to improve decision-making and revolutionize care of AIS patients in Hong Kong and globally. Clinicians will be able to utilize our results to provide the best and most cost-effective timing for initiating brace treatment.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Use of Proximal Femur Maturity Index in Guiding Brace Weaning for Adolescent Idiopathic Scoliosis.
Cheung PWH, Canavese F, Wong JSH, Luk KDK, et al · · 2025 · PMID 41210905 · DOI 10.2106/jbjs.oa.25.00191
Verify or expand the search:
- PubMed search for NCT04117334
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Bracing
Trials testing the same drug.
- NCT04500041 — Casting vs Bracing for Idiopathic Early-Onset Scoliosis · NA · active not recruiting
Other recruiting trials for Adolescent Idiopathic Scoliosis
Currently open trials in the same condition.
- NCT07249515 — Scapula and Upper Extremity Performance in Scoliosis · recruiting
- NCT07430098 — Feedback-Based Balance Training for Adolescents With Idiopathic Scoliosis · NA · active not recruiting
- NCT06680297 — Preoperative Carbohydrate Drink in Adolescent Idiopathic Scoliosis Surgery: the Impact on Safety and Enhanced Recovery · NA · recruiting
- NCT06279468 — Clinical Effectiveness of Intervertebral Disc Release in Treating Lenke 5 Adolescent Idiopathic Scoliosis · NA · recruiting
- NCT06416579 — Comparison of the Efficiency of Schroth Method and Virtual Reality Exercises in Individuals With AIS · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04117334 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The University of Hong Kong
- Last refreshed: 6 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04117334.
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