Who is sponsoring NCT04116216?

NCT04116216 is sponsored by Universidade Federal de Pernambuco.

What drugs are being tested in NCT04116216?

Interventions in NCT04116216: High frequency repetitive transcranial magnetic stimulation, Low frequency repetitive transcranial magnetic stimulation, Sham repetitive transcranial magnetic stimulation.

What condition does NCT04116216 study?

NCT04116216 studies Parkinson Disease.

Is NCT04116216 still recruiting?

NCT04116216 is currently status unknown. Last updated 4 October 2019.

Last reviewed 2019-10-04 · How we verify

NCT04116216

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

rTMS on Motor Function of Parkinson's Disease Patients With Different Phenotypes

Status unknown Phase 2 Last updated 4 October 2019

What this trial tests

Phase 2 trial testing High frequency repetitive transcranial magnetic stimulation in Parkinson Disease in 30 participants. Status unknown.

Timeline

15 October 2019

Primary endpoint
30 December 2020

30 April 2021

Quick facts

Lead sponsor	Universidade Federal de Pernambuco
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	30
Start date	15 October 2019
Primary completion	30 December 2020
Estimated completion	30 April 2021
Sites	1 location across Brazil

Drugs / interventions tested

High frequency repetitive transcranial magnetic stimulation
Low frequency repetitive transcranial magnetic stimulation
Sham repetitive transcranial magnetic stimulation

Conditions studied

Parkinson Disease — all drugs for Parkinson Disease →

Sponsor

Universidade Federal de Pernambuco — full company profile →

Who can join

40 and older, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In this study we wondered whether patients with different phenotypes of Parkinson's disease respond differently to the protocol of repetitive transcranial magnetic stimulation (rTMS) associated with physical therapy. Furthermore, the study aims to compare the effects of rTMS protocols (high and low frequency) associated with physical therapy in PD patients with different phenotypes regarding to motor performance; bradykinesia; functional mobility; balance; quality of life; perception of improvement.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Novel targeted therapies for Parkinson's disease.
Ntetsika T, Papathoma PE, Markaki I. · · 2021 · cited 78× · PMID 33632120 · DOI 10.1186/s10020-021-00279-2

Verify or expand the search:

Other trials of High frequency repetitive transcranial magnetic stimulation

Trials testing the same drug.

NCT06265922 — Cerebellar RTMS in Patients with Multiple Sclerosis · NA · completed
NCT05584124 — rTMS for Post-stroke Fatigue · NA · suspended
NCT03394560 — rTMS and Body Weight-support Treadmill Training After Incomplete Spinal Cord Injury · Phase 2 · unknown

Other recruiting trials for Parkinson Disease

Currently open trials in the same condition.

NCT07399496 — Accelerated TMS for Apathy in PD · NA · recruiting
NCT07371338 — Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients · Phase 1 · recruiting
NCT07442370 — The Effect of Functional Rotational Exercises on Fall Risk and Mobility in Parkinson's Disease Patients · NA · recruiting
NCT06848205 — Percept Transitions in FOG and PD · NA · recruiting
NCT07432958 — A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (P · Phase 2 · recruiting

Other Universidade Federal de Pernambuco trials

Trials by the same sponsor.

NCT07366411 — taVNS on Functional Mobility in People With DP · Phase 2 · not yet recruiting
NCT07132021 — Efficacy of Trans-auricular Vagus Nerve Stimulation on Upper Extremity Motor Recovery in Stroke Survivors · Phase 2 · recruiting
NCT07149233 — Effectiveness of Inspiratory Muscle Training on Sleep in Patients With Obstructive Sleep Apnea · NA · enrolling by invitation
NCT06886386 — TsDCS and Physical Therapy After Incomplete Spinal Cord Injury · NA · enrolling by invitation
NCT07523126 — EFFECT OF TRANSCUTANEOUS ELECTRONEURO-STIMULATION OF THE VAGUS NERVE ON JOINT PAIN SEQUELAE OF CHIKUNGUNYA FEVER IN THE · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04116216 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidade Federal de Pernambuco
Last refreshed: 4 October 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04116216.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing