Who is sponsoring NCT04111276?

NCT04111276 is sponsored by The University of Tennessee, Knoxville.

What drugs are being tested in NCT04111276?

Interventions in NCT04111276: Breg Osteoarthritis Brace gait fluoroscopy, Gait fluoroscopy without brace, JointVue ultrasound, Computer Tomography.

What condition does NCT04111276 study?

NCT04111276 studies Osteoarthritis, Knee.

Is NCT04111276 still recruiting?

NCT04111276 is currently completed. Last updated 12 October 2021.

Are results published for NCT04111276?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2021-10-12 · How we verify

NCT04111276

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

In Vivo Three-Dimensional Determination of Osteoarthritis Brace Effectiveness

Completed NA Results posted Last updated 12 October 2021

What this trial tests

NA trial testing Breg Osteoarthritis Brace gait fluoroscopy in Osteoarthritis, Knee in 23 participants. Completed in 6 November 2020.

Timeline

12 July 2019

Primary endpoint
6 November 2020

6 November 2020

Quick facts

Lead sponsor	The University of Tennessee, Knoxville
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	23
Start date	12 July 2019
Primary completion	6 November 2020
Estimated completion	6 November 2020
Sites	3 locations across United States

Drugs / interventions tested

Breg Osteoarthritis Brace gait fluoroscopy
Gait fluoroscopy without brace
JointVue ultrasound
Computer Tomography

Conditions studied

Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →

Sponsor

The University of Tennessee, Knoxville

Who can join

18 and older, any sex, with Osteoarthritis, Knee. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Medial Condylar Separation With Brace Primary · One day

Medial condylar separation during gait

Group	Value	95% CI
Subjects Diagnosed With Osteoarthritis of the Knee	0.60	± 1.14

Medial Condylar Separation Without Brace Primary · One day

Medial condylar separation during gait

Group	Value	95% CI
Subjects Diagnosed With Osteoarthritis of the Knee	-1.05	± 1.00

Sponsor's own description

In vivo knee kinematics will be assessed for 20 subjects that have been clinically diagnosed with substantial unicompartmental osteoarthritis (OA) by one of the surgeons of Colorado Joint Replacement; this is the location from which participants will be recruited. The objective of this study will be to analyze subjects with symptomatic unicompartmental osteoarthritis under in vivo dynamic, weight-bearing conditions using video fluoroscopy to determine if present-day OA knee braces provide separation of the femoral condyle from the tibial plateau, thus avoiding excessive loads on the degenerative compartment.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Osteoarthritis, Knee

Currently open trials in the same condition.

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NCT06488144 — Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans · Phase 3 · recruiting
NCT07386561 — Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty · NA · active not recruiting
NCT07514598 — Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA) · NA · active not recruiting
NCT07058623 — Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement · NA · recruiting

Other The University of Tennessee, Knoxville trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04111276 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by The University of Tennessee, Knoxville
Last refreshed: 12 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04111276.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing