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NCT04110405
Scaling-Up Stepped Care for Women's Mental Health in Primary Care in an LMIC
NA trial testing Stepped Care in Depression in 630 participants. Status unknown.
1 April 2023
Quick facts
| Lead sponsor | University of Illinois at Chicago |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 630 |
| Start date | 14 August 2020 |
| Primary completion | 1 April 2023 |
| Estimated completion | 1 October 2024 |
| Sites | 20 locations across Tajikistan |
Drugs / interventions tested
- Stepped Care — full drug profile →
- Standard of Care plus Healthy Lifestyle
Conditions studied
- Depression — all drugs for Depression →
- Anxiety — all drugs for Anxiety →
Sponsor
University of Illinois at Chicago
Who can join
Adults 18 to 45, female only, with Depression or Anxiety. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study examines: 1) short-term and longitudinal impacts of stepped care on women with depression and the possible roles of mediators and moderators; 2) clinic- (readiness to adopt an innovation, leadership support and climate) and provider-level (preparedness, motivation and fidelity) factors that may affect stepped care implementation; and 3) the differential impact of two implementation approaches (a clinic implementation teams versus implementation training by the research team). It utilizes Curran's hybrid effectiveness implementation design, mixed methods, and a longitudinal design with assessments at pre, 3 months, 6 months, and 12 months. A total of 18 primary care clinics, set in both rural and urban communities in Tajikistan, will be involved, with 12 delivering the intervention and 6 acting as controls. 8 providers (3 nurses, 3 peers, and 2 doctors) will be recruited at each of the 12 intervention clinics for a total of 96 providers; 35 women with depression will be recruited from each clinic for a total of 630 women.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Primary-level worker interventions for the care of people living with mental disorders and distress in low- and middle-income countries.
van Ginneken N, Chin WY, Lim YC, Ussif A, et al · · 2021 · cited 89× · PMID 34352116 · DOI 10.1002/14651858.cd009149.pub3
Verify or expand the search:
- PubMed search for NCT04110405
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Stepped Care
Trials testing the same drug.
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- NCT04747873 — Incorporating Stepped Care Approach Into e-CBT for Depression · NA · completed
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Other University of Illinois at Chicago trials
Trials by the same sponsor.
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- NCT07387705 — On Track for Wellness (OTW) Stepped Wedge Cluster Randomized Trial · Phase 1 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04110405 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Illinois at Chicago
- Last refreshed: 27 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04110405.
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