Last reviewed · How we verify
NCT04109209
Psychological Intervention For Brain Tumor Caregivers
NA trial testing Psychosocial Intervention Group in Malignant Glioma in 120 participants. Completed in 13 September 2022.
13 September 2022
Quick facts
| Lead sponsor | Massachusetts General Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 120 |
| Start date | 9 October 2019 |
| Primary completion | 13 September 2022 |
| Estimated completion | 13 September 2022 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Psychosocial Intervention Group
- Usual Care Group — full drug profile →
Conditions studied
- Malignant Glioma — all drugs for Malignant Glioma →
- Anxiety — all drugs for Anxiety →
- Caregiver Burden — all drugs for Caregiver Burden →
- Malignant Brain Tumor — all drugs for Malignant Brain Tumor →
Sponsor
Massachusetts General Hospital
Who can join
18 and older, any sex, with Malignant Glioma or Anxiety. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is testing a supportive psychosocial intervention for caregivers of people who have malignant brain tumors such as gliomas or other high-grade primary brain tumors. This study was designed because caregivers of patients with malignant brain tumors often experience physical and psychological burdens caring for their loved ones. The purpose of this study is to find out whether a program offering psychological support can help caregivers learn effective coping methods during their loved one's treatment and make the experience of being a caregiver more manageable.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Study protocol for NeuroCARE: a randomised controlled trial of a psychological intervention for caregivers of patients with primary malignant brain tumours.
Forst DA, Rhee JY, Mesa MM, Podgurski AF, et al · · 2023 · cited 2× · PMID 37678946 · DOI 10.1136/bmjopen-2022-069410 -
Improved coping and self-efficacy drive improvements in mood among caregivers of patients with primary malignant brain tumors: Results from an RCT.
Willis KD, Forst DA, Horick N, Strander SM, et al · · 2026 · PMID 42010935 · DOI 10.1093/neuonc/noag070
Verify or expand the search:
- PubMed search for NCT04109209
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Malignant Glioma
Currently open trials in the same condition.
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- NCT07447531 — T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas · NA · recruiting
- NCT06470711 — Mapping of Electrical Properties in the Brain · recruiting
- NCT05717153 — Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma · EARLY_PHASE1 · recruiting
- NCT05030298 — Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial · Phase 1 · recruiting
Other Massachusetts General Hospital trials
Trials by the same sponsor.
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- NCT06686901 — A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior · NA · not yet recruiting
- NCT05854212 — Behavioral Economics to Implement Nutrition Ranking in Food Pantries · NA · not yet recruiting
- NCT07323446 — The MIND Study: The MGH/MIT Investigation of NAC on Dysregulation · EARLY_PHASE1 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04109209 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Massachusetts General Hospital
- Last refreshed: 5 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04109209.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing