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NCT04105075

COPD in Obese Patients

Completed Last updated 3 October 2019
What this trial tests

trial in Copd in 176 participants. Completed in 20 September 2019.

Timeline
9 September 2018
Primary endpoint
10 September 2019
20 September 2019

Quick facts

Lead sponsorVoronezh N.N. Burdenko State Medical Academy
StatusCompleted
Study typeOBSERVATIONAL
Enrollment176
Start date9 September 2018
Primary completion10 September 2019
Estimated completion20 September 2019
Sites1 location across Russia

Conditions studied

Sponsor

Voronezh N.N. Burdenko State Medical Academy

Who can join

Adults 30 to 70, any sex, with Copd or Obese. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study included 176 patients with COPD. The first group included 88 normal weight patients with COPD: 71 men and 17 women, mean age 62.40 ± 8.83 years. The second group included 88 patients with COPD and obesity: 64 men and 24 women, mean age 62.94 ± 5.96 years. We assessed the frequency of COPD exacerbations in last 12 months, the severity of symptoms such as dyspnea, sputum production, fatigue. Spirometry, six-minute walk test and analysis of body tissue type composition were performed. BODE index was calculated. Levels of leptin, adiponectin, interleukins-4,6,8,10, interferon-γ, c-reactive protein (CRP), tumor necrosis factor receptor 1 (TNF-R1), tumor necrosis factor receptor 2 (TNF-R2), tumor necrosis factor alpha (TNF-α) were measured in blood serum.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Copd

Currently open trials in the same condition.

Other Voronezh N.N. Burdenko State Medical Academy trials

Trials by the same sponsor.

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Data sources for this page

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