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NCT04104958

IVF Outcome in Polycystic Ovary Syndrome Patients

Status unknown Last updated 10 January 2020
What this trial tests

trial testing qRTPCR (mRNA level). in Polycystic Ovary Syndrome in 100 participants. Status unknown.

Timeline
1 March 2020
Primary endpoint
1 December 2020
15 February 2021

Quick facts

Lead sponsorAssiut University
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment100
Start date1 March 2020
Primary completion1 December 2020
Estimated completion15 February 2021

Drugs / interventions tested

Conditions studied

Sponsor

Assiut University

Who can join

Adults 20 to 40, female only, with Polycystic Ovary Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

1. To investigate the circulating concentrations of phoenixin and their associations with BMI, the concentrations of sex hormones including (LH), (FSH), (E2), (P4), (TT) and steroid hormones enzyme in PCOS patients. 2. To detect the expression PNX and humanin in women with or without PCOS and to elucidate possible correlations with ovarian reserve and clinical outcomes after IVF-ICSI. 3. To investigate relationship between PNX, humanin expression and PI3K/AKT/mTOR and autophagy pathway as a major signaling mechanism in PCOS for targeting new prognostic and therapeutic markers. 4. The study investigates the correlation between oocyte maturity, fertilization, recent biomarkers and a variety of hormonal parameters in follicular fluid.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Polycystic Ovary Syndrome

Currently open trials in the same condition.

Other Assiut University trials

Trials by the same sponsor.

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Data sources for this page

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