NCT04104113 (HERBAL) is a Phase 2 clinical trial of Modified Xiang Bei Yang Rong Tang in Cancer, sponsored by National University of Singapore.

Who is sponsoring NCT04104113?

NCT04104113 is sponsored by National University of Singapore.

What drugs are being tested in NCT04104113?

Interventions in NCT04104113: Modified Xiang Bei Yang Rong Tang, Placebo.

What condition does NCT04104113 study?

NCT04104113 studies Cancer, Fatigue, Cognitive Impairment.

Is NCT04104113 still recruiting?

NCT04104113 is currently status unknown. Last updated 16 June 2020.

Last reviewed 2020-06-16 · How we verify

NCT04104113: HERBAL

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Health-related Quality of Life-intervention in Survivors of Breast and Other Cancers Experiencing Cancer-related Fatigue Using Traditional Chinese Medicine: The HERBAL Trial

Status unknown Phase 2 Last updated 16 June 2020

What this trial tests

Phase 2 trial testing Modified Xiang Bei Yang Rong Tang in Cancer in 80 participants. Status unknown.

Timeline

24 October 2019

Primary endpoint
30 May 2021

9 June 2022

Quick facts

Lead sponsor	National University of Singapore
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	80
Start date	24 October 2019
Primary completion	30 May 2021
Estimated completion	9 June 2022
Sites	1 location across Singapore

Drugs / interventions tested

Modified Xiang Bei Yang Rong Tang
Placebo

Conditions studied

Cancer — all drugs for Cancer →
Fatigue — all drugs for Fatigue →
Cognitive Impairment — all drugs for Cognitive Impairment →

Sponsor

National University of Singapore

Who can join

Adults 21 to 80, any sex, with Cancer or Fatigue. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is a phase 2, randomized, double-blinded, placebo-controlled trial to evaluate the efficacy and safety of a Traditional Chinese Medicine decoction, the modified Xiang Bei Yang Rong Tang, in alleviating cancer related fatigue in cancer survivors.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

A study protocol for HEalth-Related quality of life-intervention in survivors of Breast and other cancers experiencing cancer-related fatigue using TraditionAL Chinese Medicine: the HERBAL trial.
Yap NY, Loo WS, Zheng HF, Tan QM, et al · · 2020 · cited 5× · PMID 33187543 · DOI 10.1186/s13063-020-04810-4
HEalth-Related Quality of Life-Intervention in Survivors of Breast and Other Cancers Experiencing Cancer-Related Fatigue and Associated Cognitive Symptoms Using TraditionAL Chinese Medicine: The 'HERBAL' Trial.
Chan A, Chan D, Ng DQ, Zheng HF, et al · · 2025 · cited 2× · PMID 39840742 · DOI 10.1177/15347354251314514

Verify or expand the search:

Other recruiting trials for Cancer

Currently open trials in the same condition.

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Other National University of Singapore trials

Trials by the same sponsor.

NCT07519642 — Frailty Improvement Through Technology With Informal Caregiver Supported Exercise (FITWISE) for Pre-frail and Frail Comm · NA · not yet recruiting
NCT07525492 — Die-logue Program for Community Dwelling Adults: A Randomized Controlled Trial · NA · not yet recruiting
NCT07375459 — Community-based Mobile-assisted Brief Intervention for Smoking Cessation · NA · recruiting
NCT07444073 — Assessing Biological Aging in a Real-World Medical Weight Loss Program Using the LinAge2 Clinical Clock · not yet recruiting
NCT07282041 — Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis · Phase 2, PHASE3 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04104113 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National University of Singapore
Last refreshed: 16 June 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04104113.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing