Who is sponsoring NCT04103814?

NCT04103814 is sponsored by Rush University Medical Center.

What drugs are being tested in NCT04103814?

Interventions in NCT04103814: magnesium-cannabidiolic acid cream, Placebo cream.

What condition does NCT04103814 study?

NCT04103814 studies Hallux Valgus, Hallux Rigidus.

Is NCT04103814 still recruiting?

NCT04103814 is currently terminated. Last updated 15 October 2024.

Are results published for NCT04103814?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2024-10-15 · How we verify

NCT04103814

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Topical CBD Cream for Degenerative Hallux Disorders

Terminated Phase 2, PHASE3 Results posted Last updated 15 October 2024

What this trial tests

Phase 2, PHASE3 trial testing magnesium-cannabidiolic acid cream in Hallux Valgus in 11 participants. Terminated before completion.

Timeline

20 October 2019

Primary endpoint
15 May 2023

15 May 2023

Quick facts

Lead sponsor	Rush University Medical Center
Phase	Phase 2, PHASE3
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	11
Start date	20 October 2019
Primary completion	15 May 2023
Estimated completion	15 May 2023
Sites	1 location across United States

Drugs / interventions tested

magnesium-cannabidiolic acid cream — full drug profile →
Placebo cream

Conditions studied

Hallux Valgus — all drugs for Hallux Valgus →
Hallux Rigidus — all drugs for Hallux Rigidus →

Sponsor

Rush University Medical Center

Who can join

18 and older, any sex, with Hallux Valgus or Hallux Rigidus. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Hallux rigidus and hallux valgus are chronic forefoot conditions associated with pain, inflammation and functional impairment. Topical cannabidiol (CBD) cream has been shown to decrease inflammation, swelling, and pain response in arthritis models with minimal side effects, although the intervention has never been studied in hallux valgus or hallux rigidus. The purpose of this study is to determine if topical CBD cream is an effective treatment for pain secondary to hallux rigidus and hallux valgus.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Non-surgical interventions for treating osteoarthritis of the big toe joint.
Munteanu SE, Buldt A, Lithgow MJ, Cotchett M, et al · · 2024 · cited 3× · PMID 38884172 · DOI 10.1002/14651858.cd007809.pub3

Verify or expand the search:

Other recruiting trials for Hallux Valgus

Currently open trials in the same condition.

NCT07267156 — Evaluation of a New Postoperative Dressing After Hallux Valgus Surgery · NA · recruiting
NCT07378917 — Orthotic Impact on MTP Alignment in Hallux Valgus · NA · recruiting
NCT06185608 — The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Blocks · NA · recruiting
NCT06874517 — Second Toe Length and Hallux Valgus: Greek vs. Egyptian Foot · recruiting
NCT06541119 — Effect of Selective Strengthening of Peroneus Longus on Pain , Joint Alignment and Foot Function in Hallux Valgus · NA · recruiting

Other Rush University Medical Center trials

Trials by the same sponsor.

NCT07278076 — Clinical Decision-Making During FEES: The Impact of Residue Amount and Location · NA · not yet recruiting
NCT07088120 — PRECISION-CPR: PRecision-Controlled Ventilation in CPR · NA · not yet recruiting
NCT06894719 — Oral Tranexamic Acid After Total Knee Arthroplasty · Phase 4 · not yet recruiting
NCT06229392 — A Study to Evaluate the Intratumoral Influenza Vaccine Administration in Patients With Breast Cancer · Phase 1 · withdrawn
NCT07452406 — Protocolized Weaning of High-Flow Nasal Cannula in Adult Patients · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04103814 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Rush University Medical Center
Last refreshed: 15 October 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04103814.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing