NCT04103385: RISE

Reconnecting: Improving Interoception to Reduce Suicidal Ideation in the Military

Completed NA Last updated 25 April 2022

What this trial tests

NA trial testing RISE (Reconnecting to Internal Sensations and Experiences) in Suicidal Ideation in 195 participants. Completed in 22 November 2021.

Timeline

1 June 2020

Primary endpoint
22 November 2021

22 November 2021

Quick facts

Lead sponsor	Miami University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	195
Start date	1 June 2020
Primary completion	22 November 2021
Estimated completion	22 November 2021
Sites	2 locations across United States

Drugs / interventions tested

• RISE (Reconnecting to Internal Sensations and Experiences)
• RISE (Reconnecting to Individual Strength and Energy)

Conditions studied

• Suicidal Ideation — all drugs for Suicidal Ideation →
• Interoception — all drugs for Interoception →

Sponsor

Miami University

Who can join

Adults 18 to 65, any sex, with Suicidal Ideation or Interoception. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: Interoception is defined as the "sense of the physiological condition of the entire body" and is crucial for recognizing emotions and sensations (e.g., hunger, temperature, pain) and responding accordingly. The investigator's lab has conducted several independent studies and two pilot studies that support the hypothesis that disrupted interoception leads one to be disconnected from the body, and thus more able to harm the body should one desire to do so. Research suggests that interoceptive deficits may not only differentiate those who are thinking about suicide from those who engage in suicidal behavior, but it may also provide information about who is at imminent risk for suicidal behavior. The identification of novel, short-term risk factors, like interoceptive deficits, allows for the development of new treatment applications for suicide, which is important for several reasons: 1) suicide rates have increased in recent years, especially among military populations, and 2) existing treatment approaches are often ineffective, lengthy, expensive, or impractical for large-scale dissemination. This project evaluates a novel, brief intervention for interoceptive deficits and suicidal behavior with the potential to be acceptable and feasible for a military population.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.