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NCT04098991
Improving White Matter Integrity With Thyroid Hormone
trial testing Levothyroxine in Hypothyroidism in 5 participants. Completed in 8 November 2019.
8 November 2019
Quick facts
| Lead sponsor | University of Illinois at Chicago |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 5 |
| Start date | 8 November 2017 |
| Primary completion | 8 November 2019 |
| Estimated completion | 8 November 2019 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Levothyroxine (levothyroxine) — full drug profile →
Conditions studied
- Hypothyroidism — all drugs for Hypothyroidism →
Sponsor
University of Illinois at Chicago
Who can join
Adults 21 to 60, any sex, with Hypothyroidism. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Animal studies have shown that thyroid hormone can improve white matter integrity after damage to myelin, which insulates and protects nerves. It is currently unknown whether this type of repair can occur in humans. The purpose of the proposed study is to examine the impact of thyroid hormone on white matter integrity in humans using two complementary, state-of-the-art neuroimaging techniques: high angular diffusion imaging and multicomponent relaxometry.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04098991
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Levothyroxine
Trials testing the same drug.
- NCT06731764 — Novel Approaches to the Treatment of Hypothyroidism · Phase 2, PHASE3 · recruiting
- NCT06625814 — A Study of Levothyroxine and Enlicitide Decanoate (MK-0616) in Healthy Adult Participants (MK-0616-028) · Phase 1 · completed
- NCT06428097 — Levothyroxine Supplementation for Heart Transplant Recipients · Phase 1 · recruiting
- NCT05712421 — A Study Evaluation the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in P · Phase 2 · completed
- NCT05412979 — A Study Evaluating the Safety and Efficacy of Hormone Replacement Therapy With ST-1891 Compared to Levothyroxine in Pati · Phase 2 · completed
Other recruiting trials for Hypothyroidism
Currently open trials in the same condition.
- NCT07060118 — Gluten Free Diet in Hashimoto's Hypothyroidism · NA · recruiting
- NCT06757712 — Periodization Resistance Training on Quality of Life in Females With Hypothyroidism · NA · recruiting
- NCT06731764 — Novel Approaches to the Treatment of Hypothyroidism · Phase 2, PHASE3 · recruiting
- NCT06826248 — Clinical Efficacy of Darqeen Capsule for the Management of Hypothyroidism Associated with Female Reproductive Hormonal I · EARLY_PHASE1 · active not recruiting
- NCT07421869 — SNUH Immune Checkpoint Inhibitor-induced Hypothyroidism Recovery Trial · NA · recruiting
Other University of Illinois at Chicago trials
Trials by the same sponsor.
- NCT07498322 — Chicago Data-driven Opioid Use Disorder Screening, Engagement, Treatment and Planning System · NA · not yet recruiting
- NCT07387705 — On Track for Wellness (OTW) Stepped Wedge Cluster Randomized Trial · Phase 1 · not yet recruiting
- NCT07504120 — The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis · NA · not yet recruiting
- NCT07160582 — Cognitive-Motor Training for AD/ADRD Prevention · NA · not yet recruiting
- NCT07498348 — Apple Watch Evaluation of Endodontics Occupational Stress · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04098991 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Illinois at Chicago
- Last refreshed: 10 April 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04098991.
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