NCT04085640: NOCH

Obturator Nerve Block in Total Hip Arthrosplasty

Completed NA Last updated 14 December 2020

What this trial tests

NA trial testing Obturator nerve block with ropivacaine 0.2%. in Primary Total Hip Arthroplasty in 60 participants. Completed in 22 September 2020.

Timeline

14 January 2020

Primary endpoint
22 September 2020

22 September 2020

Quick facts

Lead sponsor	Clinique Medipole Garonne
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	other
Enrollment	60
Start date	14 January 2020
Primary completion	22 September 2020
Estimated completion	22 September 2020
Sites	1 location across France

Drugs / interventions tested

• Obturator nerve block with ropivacaine 0.2%.
• Obturator nerve block with isotonic saline

Conditions studied

• Primary Total Hip Arthroplasty — all drugs for Primary Total Hip Arthroplasty →

Sponsor

Clinique Medipole Garonne

Who can join

18 and older, any sex, with Primary Total Hip Arthroplasty. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Interest of obturator nerve block for analgesia in total hip arthroplasty remains controversial. This regional anesthesia procedure could provide post-operative pain relief as obturator nerve is responsible for innervation of the internal part of the hip joint capsule.

This randomized double-blind study aims to assess obturator nerve block for post-operative analgesia in total hip arthroplasty.

Before the surgery, an ultrasound guided obturator nerve block will be performed with either 20cc of saline or ropivacaine 0.2% (a long-acting local anesthetics). After regional anesthesia, a general anesthesia will be performed for intraoperative period.

This study aims to assess post-operative pain management during the first 24 hours. Ability to walk the day of the surgery will also be collected.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Obturator nerve block does not provide analgesic benefits in total hip arthroplasty under multimodal analgesic regimen: a randomized controlled trial.
   Marty P, Chassery C, Rontes O, Vuillaume C, et al · · 2021 · cited 7× · PMID 33952684 · DOI 10.1136/rapm-2021-102531