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NCT04084652: PIMP

Mycoprotein and Muscle Protein Synthetic Response

Completed NA Last updated 27 May 2022
What this trial tests

NA trial testing Mycoprotein ingestion in Anabolic Response to Mycoprotein and Micronutrient Ingeston in 24 participants. Completed in 11 December 2019.

Timeline
15 April 2019
Primary endpoint
11 December 2019
11 December 2019

Quick facts

Lead sponsorUniversity of Exeter
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingtriple
Primary purposebasic science
Enrollment24
Start date15 April 2019
Primary completion11 December 2019
Estimated completion11 December 2019
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

University of Exeter

Who can join

Adults 18 to 40, male only, with Anabolic Response to Mycoprotein and Micronutrient Ingeston. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Dietary protein is vital for the preservation of health and optimal adaptation to training. However, traditional animal proteins come with a number of economic, environmental, and ethical issues. Accordingly, there is a need to develop an understanding of the utility of more sustainable non-animal derived dietary proteins to support our nutrition. Mycoprotein, produced by Quorn Foods™, has recently been shown to stimulate a greater anabolic response within skeletal muscle compared with milk protein, suggesting its utility within sports nutrition. However, it is unclear what accounted for the greater anabolic response of mycoprotein. One explanation could be the non-protein nutrients contained within mycoprotein (e.g. fibre, carbohydrate, fat or micronutrients). Therefore, the present study will compare the muscle anabolic response between mycoprotein (MYC) as a whole food and the protein isolated from mycoprotein (PIM).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Mycoprotein ingestion within or without its wholefood matrix results in equivalent stimulation of myofibrillar protein synthesis rates in resting and exercised muscle of young men.
    West S, Monteyne AJ, Whelehan G, Abdelrahman DR, et al · · 2023 · cited 24× · PMID 36172885 · DOI 10.1017/s0007114522003087

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