NCT04081909 is a Phase 4 clinical trial of Fentanyl，Remifentanil in Intravenous Anesthesia, sponsored by Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University.

What drugs are being tested in NCT04081909?

Interventions in NCT04081909: Fentanyl，Remifentanil, Ketamine,Dexmedetomidine.

What condition does NCT04081909 study?

NCT04081909 studies Intravenous Anesthesia.

Is NCT04081909 still recruiting?

NCT04081909 is currently status unknown. Last updated 9 September 2019.

Last reviewed 2019-09-09 · How we verify

NCT04081909

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Opioid Based Anaesthesia vs Opioid Free Anesthesia in Cleft Lip, Palate ,Alveolus Surgery.

Status unknown Phase 4 Last updated 9 September 2019

What this trial tests

Phase 4 trial testing Fentanyl，Remifentanil in Intravenous Anesthesia in 60 participants. Status unknown.

Timeline

4 September 2019

Primary endpoint
4 May 2020

4 October 2020

Quick facts

Lead sponsor	Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	60
Start date	4 September 2019
Primary completion	4 May 2020
Estimated completion	4 October 2020

Drugs / interventions tested

Fentanyl，Remifentanil — full drug profile →
Ketamine,Dexmedetomidine — full drug profile →

Conditions studied

Intravenous Anesthesia — all drugs for Intravenous Anesthesia →

Sponsor

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Who can join

Adults 3 Months to 12, any sex, with Intravenous Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Peri-operative opioid administration has long been one of the three pillars of 'balanced anaesthesia',over the span of just a few years,opioids were widely used in perioperative analgesia because of pain as the fifth vital sign.However, opioid administration is not without concern and is associated with many side-effects such as constipation, urinary retention, respiratory depression and postoperative nausea and vomiting .Cleft lip,palate,alveolus are common craniofacial abnormalities and usually require surgical repair.These patients have risks for various perioperative complications due to their young age and craniofacial abnormalities. This study was designed to compare the effects of opioid based anesthesia（OBA） and opioid free anesthesia(OFA )on perioperative complications in patients with in cleft lip,palate,alveolus surgery, including respiratory depression, postoperative nausea and vomiting, hemodynamic effects, etc.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04081909 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Last refreshed: 9 September 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04081909.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing