NCT04080817 (Lexi) is a NA clinical trial of Neolexon in Aphasia, Acquired, sponsored by Ludwig-Maximilians - University of Munich.

Who is sponsoring NCT04080817?

NCT04080817 is sponsored by Ludwig-Maximilians - University of Munich.

What drugs are being tested in NCT04080817?

Interventions in NCT04080817: Neolexon, Speech therapy, Self training.

What condition does NCT04080817 study?

NCT04080817 studies Aphasia, Acquired, Stroke, Acute.

Is NCT04080817 still recruiting?

NCT04080817 is currently status unknown. Last updated 10 September 2019.

Last reviewed 2019-09-10 · How we verify

NCT04080817: Lexi

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Neolexon® Aphasia-App in Acute Aphasia After Stroke

Status unknown NA Last updated 10 September 2019

What this trial tests

NA trial testing Neolexon in Aphasia, Acquired in 70 participants. Status unknown.

Timeline

1 October 2019

Primary endpoint
1 November 2019

1 February 2020

Quick facts

Lead sponsor	Ludwig-Maximilians - University of Munich
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	70
Start date	1 October 2019
Primary completion	1 November 2019
Estimated completion	1 February 2020
Sites	1 location across Germany

Drugs / interventions tested

Neolexon
Speech therapy
Self training

Conditions studied

Aphasia, Acquired — all drugs for Aphasia, Acquired →
Stroke, Acute — all drugs for Stroke, Acute →

Sponsor

Ludwig-Maximilians - University of Munich

Who can join

18 and older, any sex, with Aphasia, Acquired or Stroke, Acute. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Up to now there is proven evidence of traditional logopedic therapy in aphasia, but recent computer-based algorithms also showed their evidence so far. Due to small and heterogenous study populations further trials are urgently needed. This prospective, randomized, clinical \& experimental controlled noninvasive study is intended to provide data for the therapy of an individual approach in aphasia patients.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Follow-Up in Aphasia Caused by Acute Stroke in a Prospective, Randomized, Clinical, and Experimental Controlled Noninvasive Study With an iPad-Based App (Neolexon®): Study Protocol of the Lexi Study.
Thunstedt DC, Young P, Küpper C, Müller K, et al · · 2020 · cited 4× · PMID 32425873 · DOI 10.3389/fneur.2020.00294
ESOC 2023 – Late Breaking Abstracts
· 2023 · cited 1×
Tablet-Assisted Speech and Language Therapy for Acute Post-Stroke Aphasia: A Randomized Clinical Trial (LEXI Study).
Wischmann J, Brasch L, Franzen J, Schwierz J, et al · · 2025 · PMID 41294376 · DOI 10.1111/ene.70443

Verify or expand the search:

Other recruiting trials for Aphasia, Acquired

Currently open trials in the same condition.

NCT07281313 — Aphasia Physical EXercise Study: Randomized Trial · NA · recruiting
NCT06842745 — Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia · Phase 2 · recruiting
NCT06092814 — tACS to Enhance Language Abilities · NA · recruiting
NCT05667480 — VR and Script Training of PWA · NA · active not recruiting
NCT05443633 — Enhancing Language Function in Aphasia · NA · recruiting

Other Ludwig-Maximilians - University of Munich trials

Trials by the same sponsor.

NCT07514520 — Decision-making, Ethical Consent, and Interactive Dialogue in Ongoing Neurocognitive Decline - DECISION · active not recruiting
NCT07504965 — Dementia-friendly Apothecaries as a Resource for Mental Heath in the Elderly · recruiting
NCT07100548 — A Qualitative Analysis of Youth Responses to Depression Education Delivered on Social Media · completed
NCT07061600 — Enhancing Depression Literacy and Reducing Stigma in Adolescents Through Social Media · NA · completed
NCT06749106 — Plaque Imaging in Routine Care to Detect Intraplaque Hemorrhage · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04080817 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ludwig-Maximilians - University of Munich
Last refreshed: 10 September 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04080817.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing