Who is sponsoring NCT04080414?

NCT04080414 is sponsored by University of Utah.

What drugs are being tested in NCT04080414?

Interventions in NCT04080414: Home-based high-intensity interval training, Home-based moderate-intensity continuous exercise.

What condition does NCT04080414 study?

NCT04080414 studies Colorectal Cancer, Colorectal Neoplasms, Colorectal Carcinoma, Colonic Neoplasms, Colonic Cancer, Rectal Neoplasms, Rectal Cancer.

Is NCT04080414 still recruiting?

NCT04080414 is currently completed. Last updated 22 March 2023.

Last reviewed 2023-03-22 · How we verify

NCT04080414

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Home-based HIIT to Improve CRC Survivorship: Feasibility and Relationship With Novel Surrogate Biomarkers of CRC Recurrence

Completed NA Last updated 22 March 2023

What this trial tests

NA trial testing Home-based high-intensity interval training in Colorectal Cancer in 7 participants. Completed in 12 February 2021.

Timeline

2 August 2019

Primary endpoint
12 February 2021

12 February 2021

Quick facts

Lead sponsor	University of Utah
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	other
Enrollment	7
Start date	2 August 2019
Primary completion	12 February 2021
Estimated completion	12 February 2021
Sites	2 locations across United States

Drugs / interventions tested

Home-based high-intensity interval training
Home-based moderate-intensity continuous exercise

Conditions studied

Colorectal Cancer — all drugs for Colorectal Cancer →
Colorectal Neoplasms — all drugs for Colorectal Neoplasms →
Colorectal Carcinoma — all drugs for Colorectal Carcinoma →
Colonic Neoplasms — all drugs for Colonic Neoplasms →

Sponsor

University of Utah

Who can join

Adults 19 to 75, any sex, with Colorectal Cancer or Colorectal Neoplasms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This 12-week, exercise study will assess the feasibility of a home-based high-intensity interval training (HIIT) program among colorectal cancer survivors and explore the impact of home-based HIIT compared to a standard home-based moderate-intensity continuous aerobic exercise program on physical outcomes linked with survival from colorectal cancer and surrogate blood markers of colorectal cancer recurrence. HIIT is a type of aerobic exercise that includes short bursts (i.e. 1-4 minutes) of vigorous exercise followed by longer periods of moderate to lower intensity exercise (i.e. 1-10 minutes). Participants in this study will be randomly assigned into a personalized home based exercise program - either high-intensity interval training (HIIT) or moderate-intensity continuous aerobic exercise (MICE). This pilot study will provide us with preliminary evidence for a larger trial aimed to compare the effectiveness of these two different types of home-based exercise programs on physical outcomes linked with survival, quality of life, and surrogate blood markers of colorectal cancer recurrence.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Exercise and colorectal cancer: prevention and molecular mechanisms.
Amirsasan R, Akbarzadeh M, Akbarzadeh S. · · 2022 · cited 38× · PMID 35945569 · DOI 10.1186/s12935-022-02670-3
Feasibility and acceptability of an mHealth, home-based exercise intervention in colorectal cancer survivors: A pilot randomized controlled trial.
Moraitis AM, Rose NB, Johnson AF, Dunston ER, et al · · 2023 · cited 8× · PMID 37347792 · DOI 10.1371/journal.pone.0287152

Verify or expand the search:

Other recruiting trials for Colorectal Cancer

Currently open trials in the same condition.

NCT07152821 — Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcino · Phase 3 · recruiting
NCT07353645 — KRAS Neoantigen Nanovaccine as Adjuvant Therapy for Colorectal Cancer/Pancreatic Cancer · Phase 1, PHASE2 · recruiting
NCT07432633 — [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications · Phase 1, PHASE2 · recruiting
NCT07523919 — Functional and Respiratory Determinants of Long-Term Colorectal Cancer Outcomes · recruiting
NCT07529301 — Functional and Respiratory Predictors of Early Postoperative Outcomes · recruiting

Other University of Utah trials

Trials by the same sponsor.

NCT07515755 — Supplemental Oxygen and Oxygen Desaturations in Colonoscopies · NA · not yet recruiting
NCT07225426 — Personalizing Financial Incentives · NA · recruiting
NCT06716411 — Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness · NA · recruiting
NCT07246538 — Positive Airway Pressure (PAP) System Evaluation in Volunteers · NA · not yet recruiting
NCT04208984 — Diversion Device With Breath Control · withdrawn

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04080414 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Utah
Last refreshed: 22 March 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04080414.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing