NCT04078243 (FIT-PH) is a clinical trial of CardioMEMS HF System in Pulmonary Hypertension, sponsored by Sheffield Teaching Hospitals NHS Foundation Trust.

Who is sponsoring NCT04078243?

NCT04078243 is sponsored by Sheffield Teaching Hospitals NHS Foundation Trust.

What drugs are being tested in NCT04078243?

Interventions in NCT04078243: CardioMEMS HF System.

What condition does NCT04078243 study?

NCT04078243 studies Pulmonary Hypertension.

Is NCT04078243 still recruiting?

NCT04078243 is currently recruiting now. Last updated 4 June 2025.

Last reviewed 2025-06-04 · How we verify

NCT04078243: FIT-PH

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Feasibility of Novel Clinical Trial Infrastructure, Design and Technology for Early Phase Studies in Patients With Pulmonary Hypertension (FIT-PH)

Recruiting now Last updated 4 June 2025

What this trial tests

trial testing CardioMEMS HF System in Pulmonary Hypertension in 120 participants. Currently enrolling.

Timeline

21 January 2020

Primary endpoint
6 January 2028

6 September 2028

Quick facts

Lead sponsor	Sheffield Teaching Hospitals NHS Foundation Trust
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	120
Start date	21 January 2020
Primary completion	6 January 2028
Estimated completion	6 September 2028
Sites	1 location across United Kingdom

Drugs / interventions tested

CardioMEMS HF System

Conditions studied

Pulmonary Hypertension — all drugs for Pulmonary Hypertension →

Sponsor

Sheffield Teaching Hospitals NHS Foundation Trust

Who can join

18 and older, any sex, with Pulmonary Hypertension. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Prospective, open-label, observational study to evaluate the safety and feasibility of using pulmonary artery pressure (PAP) monitors and wearable activity monitors in patients with pulmonary hypertension (PH).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Positioning Imatinib for Pulmonary Arterial Hypertension: A Dose-Finding Phase 2 Study.
Rothman AMK, Villar SS, Middleton J, Roussakis AA, et al · · 2025 · cited 14× · PMID 40080796 · DOI 10.1164/rccm.202410-1929oc
Digital Data Collection Reduces Terminal Digit Bias in Haemodynamic and Physical Activity Measures in Pulmonary Arterial Hypertension
Rothman AM, Wason J, Toshner M. · · 2025 · DOI 10.1101/2025.05.21.25328105

Verify or expand the search:

Other trials of CardioMEMS HF System

Trials testing the same drug.

NCT05284955 — Screening for Advanced Heart Failure IN Stable outPatientS - The SAINTS Study (SAINTS B) · Phase 4 · unknown
NCT06306573 — CardioMEMS HF System Real-World Evidence Post-Approval Study · enrolling by invitation

Other recruiting trials for Pulmonary Hypertension

Currently open trials in the same condition.

NCT07179380 — Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension · Phase 3 · recruiting
NCT07073820 — A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have P · Phase 2 · recruiting
NCT06351345 — 129 Xenon Imaging in Patients Treated With Sotatercept · Phase 2 · recruiting
NCT07187206 — Safety and Efficacy of FETO in CDH Phase III · Phase 3 · recruiting
NCT07206173 — Londrina Activities of Daily Living Protocol in Pulmonary Hypertension · recruiting

Other Sheffield Teaching Hospitals NHS Foundation Trust trials

Trials by the same sponsor.

NCT07407712 — Better Outcomes Through Optimal Sleep in Surgical Training · NA · recruiting
NCT07172555 — Virtual Dietetic Interventions in Patients With Coeliac · NA · recruiting
NCT06310993 — Exercise to Boost Immunity in Advanced Cancer · NA · not yet recruiting
NCT06905405 — The Use of Advanced Imaging in HFpEF · recruiting
NCT06633627 — Neurological Responses in Patients with Dentine Hypersensitivity · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04078243 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Sheffield Teaching Hospitals NHS Foundation Trust
Last refreshed: 4 June 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04078243.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing