NCT04077697 (ITBA) is a clinical trial of RT-PCR for influenza in Invasive Pulmonary Aspergillosis, sponsored by Centre Hospitalier Universitaire, Amiens.

Who is sponsoring NCT04077697?

NCT04077697 is sponsored by Centre Hospitalier Universitaire, Amiens.

What drugs are being tested in NCT04077697?

Interventions in NCT04077697: RT-PCR for influenza.

What condition does NCT04077697 study?

NCT04077697 studies Invasive Pulmonary Aspergillosis, Morality.

Is NCT04077697 still recruiting?

NCT04077697 is currently completed. Last updated 4 September 2019.

Last reviewed 2019-09-04 · How we verify

NCT04077697: ITBA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical and Prognostic Comparisons Between Invasive Pulmonary Aspergillosis With or Without Invasive Tracheobronchitis During Severe Influenza: a Retrospective Multicenter Cohort Study.

Completed Last updated 4 September 2019

What this trial tests

trial testing RT-PCR for influenza in Invasive Pulmonary Aspergillosis in 35 participants. Completed in 16 July 2019.

Timeline

1 July 2019

Primary endpoint
16 July 2019

16 July 2019

Quick facts

Lead sponsor	Centre Hospitalier Universitaire, Amiens
Status	Completed
Study type	OBSERVATIONAL
Enrollment	35
Start date	1 July 2019
Primary completion	16 July 2019
Estimated completion	16 July 2019
Sites	1 location across France

Drugs / interventions tested

RT-PCR for influenza

Conditions studied

Invasive Pulmonary Aspergillosis — all drugs for Invasive Pulmonary Aspergillosis →
Morality — all drugs for Morality →

Sponsor

Centre Hospitalier Universitaire, Amiens

Who can join

18 and older, any sex, with Invasive Pulmonary Aspergillosis or Morality. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Invasive tracheobronchial aspergillosis (ITBA) is an uncommon, but severe clinical form of Invasive Pulmonary Aspergillosis (IPA) in which the fungal infection is entirely or predominantly confined to the tracheobronchial tree. In view of the limited data concerning critically ill patients admitted to the intensive care unit (ICU) with severe influenza associated with ITBA, the investigators decided to evaluate the differences between the clinical presentations of two invasive infections: ITBA and IPA without tracheobronchial involvement (No ITBA).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Invasive Tracheobronchial Aspergillosis in Critically Ill Patients with Severe Influenza. A Clinical Trial.
Nyga R, Maizel J, Nseir S, Chouaki T, et al · · 2020 · cited 52× · PMID 32407157 · DOI 10.1164/rccm.201910-1931oc

Verify or expand the search:

Other recruiting trials for Invasive Pulmonary Aspergillosis

Currently open trials in the same condition.

NCT07238114 — Liver Cirrhosis Patients With Invasive Pulmonary Aspergillosis: in Depth Understanding Clinical Host Risk Factors · active not recruiting
NCT06537726 — Breath Analysis for the Detection of Invasive Fungal Infections · recruiting
NCT05860387 — Early Diagnosis of Invasive Lung Aspergillosis · recruiting

Other Centre Hospitalier Universitaire, Amiens trials

Trials by the same sponsor.

NCT07354568 — Prognosis of Patients With Mixed Cardiogenic-Vasoplegic Shock · recruiting
NCT07071662 — Induction of Labor in Breech Presentation · completed
NCT06909487 — Clinical Characterization of Very and Extremely Preterm Infants Who Received Excess Erythrocyte Transfusions With Respec · completed
NCT07037719 — Automatic Detection of Eligible Patients to RAUC Protocol (RAUCISABLE) · recruiting
NCT06996145 — Study of the Isometry of the Anterior Cruciate Ligament From the Center of the Native MRI Insertion Reported on Dynamic · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04077697 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire, Amiens
Last refreshed: 4 September 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04077697.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing