Last reviewed · How we verify
NCT04076709: RELAX-LAP
Cardiovascular Effects of Muscle Relaxation During Laparoscopic Surgery
NA trial testing goal directed anaesthesia in Hemodynamic Instability in 34 participants. Completed in 27 March 2025.
26 March 2025
Quick facts
| Lead sponsor | Leiden University Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 34 |
| Start date | 1 September 2020 |
| Primary completion | 26 March 2025 |
| Estimated completion | 27 March 2025 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- goal directed anaesthesia
Conditions studied
- Hemodynamic Instability — all drugs for Hemodynamic Instability →
Sponsor
Leiden University Medical Center
Who can join
18 and older, any sex, with Hemodynamic Instability. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Many surgical procedures are performed using the laparoscopic approach. However, insufflation of the abdomen (pneumoperitoneum) has detrimental hemodynamic effects. The investigators intend to investigate the effect of deep neuromuscular block and nociception guided anaesthesia on hemodynamic variables during pneumoperitoneum for lower abdominal laparoscopic surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Deep neuromuscular blockade in adults undergoing an abdominal laparoscopic procedure.
Bijkerk V, Jacobs LM, Albers KI, Gurusamy KS, et al · · 2024 · cited 2× · PMID 38288876 · DOI 10.1002/14651858.cd013197.pub2
Verify or expand the search:
- PubMed search for NCT04076709
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hemodynamic Instability
Currently open trials in the same condition.
- NCT07494955 — "Effect of Pre-Spinal Mindfulness-Based Breathing Exercise on Hemodynamic Response in Elective Cesarean Section" · NA · recruiting
- NCT07383220 — Effect of Electrical Stimulation and Exercise on Blood Flow in Patients With Resistant High Blood Pressure · NA · recruiting
- NCT07246148 — NOn-inVAsive Blood Pressure Monitoring in Intracranial Aneurysm Embolization · NA · recruiting
- NCT06828575 — Evaluation of the Success of Artificial Intelligence Models in Interpreting Arterial Waveform Analysis Data · recruiting
- NCT05893420 — A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning · NA · active not recruiting
Other Leiden University Medical Center trials
Trials by the same sponsor.
- NCT07312565 — Occurrence of Abdominal Aortic Aneurysms in Patients With Aneurysmal Subarachnoid Hemorrhage · not yet recruiting
- NCT07090343 — Semaglutide in Patients Undergoing Transcatether Aortic Valve Replacement · Phase 3 · not yet recruiting
- NCT07498738 — Making Diabetes Care Fit for Young Adults Living With Type 1 Diabetes: Observations, Reflections and Expert Opinions · NA · not yet recruiting
- NCT06545292 — Microsampling for Therapeutic Drug Monitoring of Oral Oncolytics in Oncology Patients · NA · recruiting
- NCT07021495 — SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY) · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04076709 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Leiden University Medical Center
- Last refreshed: 2 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04076709.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing