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NCT04075851

The Prevalence of Serum Thyroid Hormone Autoantibodies in Autoimmune Thyroid Diseases

Status unknown Last updated 14 April 2021
What this trial tests

trial in Autoimmune Thyroid Disease in 600 participants. Status unknown.

Timeline
1 August 2019
Primary endpoint
1 August 2022
1 August 2022

Quick facts

Lead sponsorShandong Provincial Hospital
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment600
Start date1 August 2019
Primary completion1 August 2022
Estimated completion1 August 2022
Sites1 location across China

Conditions studied

Sponsor

Shandong Provincial Hospital

Who can join

Adults 18 to 65, any sex, with Autoimmune Thyroid Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Thyroid hormone autoantibodies(THAA) in serum can Interfere radioimmunoassay for the determination of free thyroid hormones. Thyroid function test plays a key role in the diagnosis and treatment of autoimmune thyroid disease (AITD), and abnormal examination results in misdiagnosis and mistreatment. At present, the epidemiological results of THAA in AITD are inconsistent, and the pathogenesis has not been clarified. However, there is no relevant research on THAA in China. This project intends to collect AITD patients and healthy people, detecting THAA, at the same time testing thyroid function and thyroid autoantibodies, definiting positive rate of THAA in AITD patients, observing the effect of common therapeutic drugs for AITD on THAA, investigating the rule of THAA influencing thyroid function test results .This project will provide the basis and method for how to effectively avoid THAA interfering with thyroid function test.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Medical Applications of Molecular Biotechnologies in the Context of Hashimoto's Thyroiditis.
    Trovato M, Valenti A. · · 2023 · cited 1× · PMID 37371008 · DOI 10.3390/diagnostics13122114

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Other Shandong Provincial Hospital trials

Trials by the same sponsor.

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