NCT04074642 (FIRST) is a NA clinical trial of Neurosurgery in Pituitary Adenoma, sponsored by Centre Hospitalier Universitaire de Nice.

Who is sponsoring NCT04074642?

NCT04074642 is sponsored by Centre Hospitalier Universitaire de Nice.

What drugs are being tested in NCT04074642?

Interventions in NCT04074642: Neurosurgery.

What condition does NCT04074642 study?

NCT04074642 studies Pituitary Adenoma.

Is NCT04074642 still recruiting?

NCT04074642 is currently completed. Last updated 24 March 2026.

Last reviewed 2026-03-24 · How we verify

NCT04074642: FIRST

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

OCT-angiography as a Pronostic Marker for Visual Impairment in Patients Undergoing Neurosurgery for Compressive Macroadenoma : a Prospective Study.

Completed NA Last updated 24 March 2026

What this trial tests

NA trial testing Neurosurgery in Pituitary Adenoma in 21 participants. Completed in 22 February 2023.

Timeline

14 November 2019

Primary endpoint
22 February 2023

22 February 2023

Quick facts

Lead sponsor	Centre Hospitalier Universitaire de Nice
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	21
Start date	14 November 2019
Primary completion	22 February 2023
Estimated completion	22 February 2023
Sites	2 locations across France

Drugs / interventions tested

Neurosurgery

Conditions studied

Pituitary Adenoma — all drugs for Pituitary Adenoma →

Sponsor

Centre Hospitalier Universitaire de Nice

Who can join

18 and older, any sex, with Pituitary Adenoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to assess accurancy of OCT angiography as a pronostic marker for patients undergoing neurosurgery for compressiver macroadenoma as compared with visual acuity, visual field and OCT.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Benefit of Optical Coherence Tomography-Angiography in Patients Undergoing Transsphenoidal Pituitary Adenoma Surgery: A Prospective Controlled Study.
Toumi E, Almairac F, Mondot L, Themelin A, et al · · 2024 · cited 5× · PMID 39202235 · DOI 10.3390/diagnostics14161747

Verify or expand the search:

Other trials of Neurosurgery

Trials testing the same drug.

NCT06615271 — Pressure Injuries in the Operating Room and Their Perioperative Incidence in Patients Undergoing Neurosurgery. · recruiting
NCT05264012 — Incidence, Risk Factors and Impact of Significant Pain in Patients Undergoing Neurosurgery · completed

Other recruiting trials for Pituitary Adenoma

Currently open trials in the same condition.

NCT04569591 — DDAVP for Pituitary Adenoma · NA · recruiting
NCT06831461 — Proton Versus Photon Radiotherapy in Adults With Primary Brain Tumors · NA · recruiting
NCT06973824 — A Twenty-years' Experience in Pituitary Disease. · recruiting
NCT06679816 — Hydrocortisone in Hormone Replacement Therapy for Large Pituitary Neuroendocrine Tumors · Phase 4 · recruiting
NCT06584123 — Molecular Pituitary Imaging Using 18F-FET PET · NA · recruiting

Other Centre Hospitalier Universitaire de Nice trials

Trials by the same sponsor.

NCT05897996 — Percutaneous Anastomosis Creation for Hemodialysis Access · NA · withdrawn
NCT07499869 — INNOVATIVE BENEFITS OF A 4D VIRTUAL SIMULATOR · NA · not yet recruiting
NCT07492251 — Upadacitinib in Adult Patients With Erosive Mucosal Lichen Planus and Lichen Planopilaris: a Prospective Multicenter Ran · Phase 2 · not yet recruiting
NCT07511608 — Development of a New Technique for Quantifying Mitochondrial DNA in Single Muscle Fibers · NA · not yet recruiting
NCT07582406 — Codesign, Physical Activity, and Seniors · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04074642 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Nice
Last refreshed: 24 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04074642.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing