NCT04071964 is a clinical trial in Colorectal Cancer, sponsored by Centre hospitalier de l'Université de Montréal (CHUM).

Who is sponsoring NCT04071964?

NCT04071964 is sponsored by Centre hospitalier de l'Université de Montréal (CHUM).

What condition does NCT04071964 study?

NCT04071964 studies Colorectal Cancer.

Is NCT04071964 still recruiting?

NCT04071964 is currently active, enrolled. Last updated 16 May 2024.

Last reviewed 2024-05-16 · How we verify

NCT04071964

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Gut Microbiota, Anastomotic Leak and Colorectal Cancer

Active, enrolled Last updated 16 May 2024

What this trial tests

trial in Colorectal Cancer in 300 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

9 July 2019

Primary endpoint
9 July 2025

9 July 2025

Quick facts

Lead sponsor	Centre hospitalier de l'Université de Montréal (CHUM)
Status	Active, enrolled
Study type	OBSERVATIONAL
Enrollment	300
Start date	9 July 2019
Primary completion	9 July 2025
Estimated completion	9 July 2025
Sites	1 location across Canada

Conditions studied

Colorectal Cancer — all drugs for Colorectal Cancer →

Sponsor

Centre hospitalier de l'Université de Montréal (CHUM)

Who can join

18 and older, any sex, with Colorectal Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a prospective study evaluating the relation between the gut microbiota composition, intestinal healing after colorectal surgery and colorectal cancer behavior. Our hypothesis is that the gut microbiota composition could predict poor intestinal healing in colorectal surgery, and that the gut microbiota might have an impact on colorectal cancer clinical behavior and may predict disease outcomes.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Gut microbiota: impacts on gastrointestinal cancer immunotherapy.
Lau HCH, Sung JJ, Yu J. · · 2021 · cited 42× · PMID 33435800 · DOI 10.1080/19490976.2020.1869504
Bidirectional effects of intestinal microbiota and antibiotics: a new strategy for colorectal cancer treatment and prevention.
Zhang W, Zhang J, Liu T, Xing J, et al · · 2022 · cited 10× · PMID 35661254 · DOI 10.1007/s00432-022-04081-3

Verify or expand the search:

Other recruiting trials for Colorectal Cancer

Currently open trials in the same condition.

NCT07152821 — Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcino · Phase 3 · recruiting
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NCT07432633 — [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications · Phase 1, PHASE2 · recruiting
NCT07523919 — Functional and Respiratory Determinants of Long-Term Colorectal Cancer Outcomes · recruiting
NCT07529301 — Functional and Respiratory Predictors of Early Postoperative Outcomes · recruiting

Other Centre hospitalier de l'Université de Montréal (CHUM) trials

Trials by the same sponsor.

NCT06735638 — Outside the Cage (OTC) Robotic Esophagectomy · Phase 1 · not yet recruiting
NCT07533253 — Rescue Distal Thrombectomy in Treatment for Persistent Distal Occlusions · NA · not yet recruiting
NCT05225272 — Effectiveness of an Enhanced Recovery After Surgery Protocol in Patients Undergoing On-pump Cardiac Surgery · not yet recruiting
NCT07497061 — Comparison of Two Surgical Techniques for the Treatment of Trigger Fingers: Longitudinal Opening Versus Complete A1 Pull · NA · not yet recruiting
NCT07196410 — KAN-004 for Immune-Related Diarrhea or Colitis · Phase 1 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04071964 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre hospitalier de l'Université de Montréal (CHUM)
Last refreshed: 16 May 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04071964.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing