Who is sponsoring NCT04067089?

NCT04067089 is sponsored by Hospital do Coracao.

What drugs are being tested in NCT04067089?

Interventions in NCT04067089: TAVR - Transcatheter aortic valve replacement, Surgical aortic valve replacement.

What condition does NCT04067089 study?

NCT04067089 studies Aortic Stenosis.

Is NCT04067089 still recruiting?

NCT04067089 is currently status unknown. Last updated 2 March 2023.

Last reviewed 2023-03-02 · How we verify

NCT04067089: TEAm-BR

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Treatment of Aortic Stenosis in Brazil: Cost-Utility Analysis of TAVI vs SAVR

Status unknown NA Last updated 2 March 2023

What this trial tests

NA trial testing TAVR - Transcatheter aortic valve replacement in Aortic Stenosis in 126 participants. Status unknown.

Timeline

10 December 2018

Primary endpoint
13 September 2023

31 December 2023

Quick facts

Lead sponsor	Hospital do Coracao
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	126
Start date	10 December 2018
Primary completion	13 September 2023
Estimated completion	31 December 2023
Sites	1 location across Brazil

Drugs / interventions tested

TAVR - Transcatheter aortic valve replacement
Surgical aortic valve replacement

Conditions studied

Aortic Stenosis — all drugs for Aortic Stenosis →

Sponsor

Hospital do Coracao

Who can join

70 and older, any sex, with Aortic Stenosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

TEAM-Br is a randomized, prospective, cost-utility study comparing transcatheter aortic valve implantation (TAVI) versus surgical aortic vale replacement in Brazil. The study is sponsored by the national Minister of Health, through PROADI-SUS (Programa de Apoio ao Desenvolvimento Institucional do SUS).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Transcatheter versus surgical aortic valve replacement in patients with aortic stenosis with a small aortic annulus: A meta-analysis with reconstructed time to event data.
Awad AK, Otmani Z, Aly Yassin MN, Amin AM, et al · · 2025 · cited 2× · PMID 39840253 · DOI 10.1016/j.ijcha.2024.101578

Verify or expand the search:

Other recruiting trials for Aortic Stenosis

Currently open trials in the same condition.

NCT07197736 — DELINEATE-Prospective · recruiting
NCT07230964 — Correlation Between an Impedance Cardiography Test for Decompensation and the Development of Left Ventricular Replacemen · NA · recruiting
NCT07205068 — Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and P · NA · recruiting
NCT07052071 — Impact of Transcatheter Aortic Valve Implantation (TAVI) on the Gut Microbiota in Patients With Aortic Valve Stenosis · recruiting
NCT07144189 — AI Assessment of Low-Gradient Aortic Stenosis Severity Based on Echocardiography · recruiting

Other Hospital do Coracao trials

Trials by the same sponsor.

NCT07534163 — III Brazilian Registry of Heart Failure · not yet recruiting
NCT07129733 — Oral Care Layered Enhancement for Improved Oral Hygiene in Intensive Care Units · NA · not yet recruiting
NCT07037524 — Low Dose Radiotherapy for Heart Failure · Phase 1, PHASE2 · not yet recruiting
NCT06546137 — National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Un · recruiting
NCT06547892 — Use of Vasopressin in Patients at High Risk of Acute Kidney Injury Admitted to the ICU · Phase 2 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04067089 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Hospital do Coracao
Last refreshed: 2 March 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04067089.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing